Discover and read the best of Twitter Threads about #CytoPath

Most recents (7)

🚨 Ever find yourself in need of a cellular cell block for #cytopath workup? Here is my "bulletproof" way of getting it!

You'll need:
1. Conical vial (lab)
2. Sheep's agar (micro)
3. Plating loop (micro)
4. Plasma/Thrombin (blood bank)
5. Wrapping paper (histo)

1/5

#pathology Image
1. Spin down your fluid in a conical vial at high rpm (~1200) for 6-8 mins and remove supernatant

You'll have a soft slurry.

2. Add 3 drops plasma, 3 drops thrombin and spin again to form clot

#pathology #cytopath
2/5 Image
3. Cut out 2 squares of agar

4. In one square, scrape away a shallow "bowl" to place your clotted cell slurry

5. In the other square, trim in 1/2 and use the thin flap to cover the slurry in an agar sandwich. Agar protects pellet from dissolution!

#pathology #cytopath
3/5 ImageImageImage
Read 5 tweets
Hi #pathology tweeples! I just realized that the callus I have on my pinky is from using it to steady my hand as I dot πŸ˜‚(with my green pen of course πŸ˜‰). I must dot A LOT! πŸ’ͺπŸ”¬

I have some #path (mostly) dotting related questions out of curiosity.

@BIDMCpath Image
The #pathology tweeples have very strong opinions about dotting pen color! My tweet is inspired by this from @Chucktowndoc
Does anyone else have a dotting pen-induced callus? (Just me? I hope I'm not alone. 🀞😊)
Read 11 tweets
🀩I am constantly marveled by the endless ways in which we #Pathology and #LabMedicine, can use Twitter to engage, share, support & learn from each other. Here is the link to my presentation that celebrates the unlimited opportunities to harness TwitterπŸ‘‰πŸ½
bit.ly/39kA627 Image
Like the #SolarEclipse that occurred in August 2017, to me, Twitter has been a community wide experience of marveling a visual process that can create a burst of awe at an organic velocity. It's really exciting to be engaged in this global experience. Image
#AcademicTwitter is using Twitter at the University and Research setting to teach. It has wide range benefits and I recommend reading the following article written by @soragnilab and @Aiims1742 published in @nature that describes this phenomenon. doi.org/10.1038/s41568… ImageImage
Read 12 tweets
1/
#Melanoma can look like anything: a #Tweetorial

Most melanomas are fairly easy to recognize but the outliers are pretty crazy.

Like this example with signet ring cells πŸ‘‡πŸΎπŸ‘‡πŸΎ
Read 17 tweets
1/2020 Massive pericardial effusion in an elderly male. Metastatic lung adenocarcinoma. #cytology #CytoPath #cellblock #lungca Pap stain, MGG, cell block and IHC.
1. Multilayered cell balls, smooth outlines, psammoma body 2. Acini in CB @kriyer68 @smlungpathguy @VijayPatho ImageImage
@kriyer68 @smlungpathguy @VijayPatho @drsys02 @Swathiprabhu5 @pathridle_susan @nandishvs * Reactive mesothelial cells can show atypia & proliferation spheres, however - knobby oultline
* Proliferation spheres (cell balls) are solid with stromal cores in mesotheioma unlike carcinoma
* Mesothelial cells: peripheral condensed cytoplasm, vacuoles (intercellular windows) Image
* PsB in pleural and pericardial effusions are usually seen in malignant effusions - thyroid, ovary, lung etc.
* In peritoneal effusion however, PsB may be associated with benign mesothelial hyperplasia, endometriosis etc
* Not all ca. show cell balls- SCC, ILC, Signet ring ca
Read 5 tweets
Painless hemiscrotal mass in a child, complex hydrocele on ultrasound.

Testis mass + smear... Fight!

#pedipath #gupath #cytopath
Rhabdomyosarcoma is indeed the top-level diagnosis... but more importantly, what type??

Note: several H&E patterns here that correspond nicely to the patterns on cytology.

#pedipath #gupath #pathology
Note the multiple patterns here - and see how they relate to myogenin staining.
This is an uncommon example of mixed-histology rhabdomyosarcoma.

Classic Embryonal - variable myogenin
Dense Emb/Solid Alveolar - strong, diffuse myogenin
Sclerosing - Weak/absent myogenin

#pedipath
Read 5 tweets

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