- MAGNESIUM MEGA THREAD -

Looking for the UNFAIR advantage? 🏋️

I’ll reveal it to you now...

✨🧬 HOW TO MAXIMIZE ATHLETIC & WORKOUT PERFORMANCE THROUGH... THE POWERS OF MAGNESIUM 🧬✨ Image
Read everything, i’ll share with you a protocol + a biohack to enhance workout performance at the end
——

So today’s ⚽️ training menu included:

A 2 hour, ⚽️ session including sprinting, agility & explosiveness work in the morning.

DELICIOUS!
Ngl I was DEAD after it, went directly to my fridge for kefir.

However... PM gym session was pending...

I thot that the workout would be a “go thru the motions”, fatiguing

And more exhausting than usual type of workout

But holy!
I FELT LIKE GODDAMN ZEUS!!!!! Felt EVEN MORE stronger, lighter, agile-er & more energized than usual.

I attribute this to a single change I did in my preworkout formula:

Not cacao. Not kefir. Not maca. Not MCTs. It was...
MAGNESIUM!

The most VITAL & IMPRESCINDIBLE nutrient for you, ATHLETE.

In this thread you’ll discover how to MAXX your performance with MAGNESIUM and...

6 ways MAG SKYROCKETS your ATHLETICISM.

Enjoy it.
1. GLYCOGEN BOOST 🍯

As we know, Anaerobic exercise (lifting, sprints,,, explosive shit) demands a lot of glycogen.

However, it’s rapidly depleted during the acute phase of exercise, and your body NEEDS MORE FUEL. Image
Your liver donates it’s glycogen reserves and triggers gluconeogenesis; blood flow carries them to your MUSCLES.

That Glucose gets INTO your muscle cells thx to GLUT-4; the main glucose transporter in your muscles. Image
GLUT-4 expression SKYROCKETS during & after exercise in order to fulfill the HIGH GLUCOSE DEMAND

No GLUT-4, no party after muscle glycogen is depleted.

Keep reading. Here’s where MAGNESIUM COMES IN Image
Mg IMPROVES GLUT-4 expression AND modulates insulin activity in the GLUT-4 receptor.

This allows MORE GLUCOSE to get into your muscles, hence,

allowing GREATER GLYCOGEN STORES = more fuel = BETTER PERFORMANCE.

BUT If you’re deficient on Mag? Your GLUT 4 activity DECREASES. Image
Now... pay close attention to this:

Some subjects received MgSO4 (Mg Sulfate) as a “preworkout”, some not.

THOSE WHO RECEIVED MAGNESIUM?

HAD A TWO FOLD (400% V 800%!) HIGHER MUSCLE GLYCOGEN CONTENT.

TWO FUCKING FOLD ImageImage
omg statues can speak 😳😱
2. LACTATE BUILDUP - DELAYED! ⏰

ah yes, our good friend lactate, very responsible for that “burn” you get during ANAEROBIC exercises (deadlift, pull ups, squats, sprints)

but... how do you produce it?
You see, the reason you feel the “burn” in exercises such as a squat, a curl, or a circuit, is because LACTATE is a BYPRODUCT of glucose utilization.

When your fast twitch muscle fibers use glucose, that glucose gets oxidized INTO PYRUVATE

Then, PYRUVATE gets converted into.... ImageImage
LACTATE, faster than your body can handle it.

This increases lactate concentrations, hence, THE BURN! Sinple really

The more glucose you use? The more lactate you will produce.

(this is why being a mtabolic flexible athltee is VITAL. thread on this later)

Now, keep reading...
Imagine if YOU could delay the LACTATE BUILDUP. if you could workout LONGER (and better) without “BURNING”...

sounds like a dream... how could you do that....

🤔🤔🤔🤔🤔🤔🤔🤔🤔
EXACTLY WITH MOTHAGUCKING MAGNESUIM

In the same@paper , magnesium DELAYED MUSCLE LACTATE RISE for...

45 MINUTES during the SAME EXERCISE INTENSITY!!!!!!!!!!!!1!!!!

you’d still be sprinting & running while your opponents are drowning in lactate ImageImage
On another note,

Lactate function goes way beyond than only the “burn” - Induces BDNF, regulates the CNS, and is a FUEL for your brain.

A lot of the cognitive benefits from exercise are thanks to lactate. Man i love this molecule
“Lactate is the most important gluconeogwnic precursor in the body. About 30% of ALL GLUCOSE USED IN EXERCISE, comes from recycling lactate to glucose”

Amazing.

ps: lactate is NOT 100% responsible 4 the burn, hydrogen ions accumulating, calcium, inflammation, ALSO CONTRIBUTE
3. MITOCHONDRIAL IMPROVEMENT 🧬

Thnks to the oxygen demand & oxidative stress from exercise, your MITOCHONDRIA ALSO BREAKS DOWN -not only your muscle fibers-.

This will trigger the “MITOCHONDRIAL BIOGENESIS” route.

A self-renewal route where NEW & STRONGER mitochondria are - Image
created from the already existing ones.

This increases your mitochondrial:

- Oxidative phosphorylation capacity (hence a faster & better ATP production)
- “oxidative stress treshold”; they can handle more oxidative stress without breaking down
- and how fast they+you recover
Like muscle protein synthesis BUT for your MITOCHONDRIA.

However, most enzymes & proteins in this process...

- NEED MAGNESIUM TO WORK (cofactor)

For ex, the efficacy of the DNA Ligase III group (enzymes; repair mtDNA), is HIGHLY DEPENDANT ON MAGNESIUM
DNA Ligases follow a 3 step process, specifically, 3 phosphoryl transfers. These 3 "steps" need Magnesium as a cofactor. Low magnesium = low DNA ligase efficacy = shitty repair = shitty mitochondrial biogenesis

(DNA Ligase repairing ADN terrific right) ImageImage
NO MAGNESIUM = SHITTY MITOCHONDRIAL BIOGENESIS

= SHITTY MITOCHONDRIAL GAINZ.

YOU’LL PROGRESS SLOWER WITHOUT MAG.

YOUR ENDURANCE, STRENGTH & OVERALL FITNESS WONT PROGRSES AS YOU DESERVE

FUCK THAT.
improving your mitochondria is CRITICAL for cognition, energy, athleticism, longevity and definitely for just feeling better.

Remember: Improve your mitochondria and you'll improve how much energy you will create and use from food. (and how well you fight the 🦠).
4. ATP & ENERGY PRODUCTION

ah yes, ATP. the energy currency of the cell, the fuel used during the first seconds of exercise.

those first warm up drills? that sprint to the school bus? when you start running after you robbed the bank?

USE SOLELY STORED ATP! however... Image
ATP is useless without Magnesium. What we call ATP, in reality, it's a ATP+magnesium complex. ATP must bind to a magnesium ion to be biologically active, creating Mg+2-ATP. ImageImage
Do you realize that your cell's energy currency is "useless" without magnesium? Your cells don't work efficiently without it. Literally your body depends on magnesium to work.

Another point is energy metabolism. We know that many of the enzymes in gluconeogenesis AND -
- in cellular respiration (ATP production process) are VERY sensitive to magnesium, but specifically the glycolytic enzymes and the enzymes in Krebs.

A lot of the Krebs enzymes NEED MAGNESIUM TO WORK; Isocitrate dehydrogenase, a-Ketoglutarate (!!!), 2-oxoglutarate,
pyruvate dehydrogenase just to name a few.

biochemical-pathways.com/#/map/1
 
For ex, isocitrate dehydrogenase regulates how fast the isocitrate (a citrate isomer) loses a carbon to form the five-carbon molecule α-ketoglutarate, through oxidative DECARBOxilation

If there’s no mag?
This enzyme IS DOWNREGULATED.
 
Low magnesium = slower energy metabolism. FUCK THAT, YOU WANT A FAST ATP PRODUCTION EVEN IF YOU DEPLETE IT ALL.

You achieve that with magnesium.
Magnesium is VITAL for mitochondrial health, I mean mitochondria are your magnesium intracellular stores. That should tell you something. ImageImage
I'll end this point with this based quote: "Energy production depends upon cellular Mg status, since Mg-ATP is the direct molecule used in all physical activities."
5. RECOVERY 😴 (Sleep, Stress, Parasympathetic NS)

Read carefully, bcos if you’re serious about your progress in fitness / as an athlete/bodybuilder/whatever...

Your recovery MUST be perfect. And by recovery I don't mean "oh bro don't train the same muscle every -
- day!!" "bro you must rest 48hrs before hitting the same muscle again bro"

Bullshit.

REAL recovery will give you the strength & energy you need to do that.

And most of you know that magnesium is vital for recovery, but, you dont know the HOW.

let's discover it. 😈
We know that you, as an athlete, will have an excess of Oxidative Stress (inflammation), and it must be countered by your all mighty ANTIOXIDANT NETWORK:

Glutathione Reductase, Peroxide Dismutase, Melatonin (!!!), etc

If you're feeling more fatigued & sore than normal? ImageImageImage
It means that ur antioxidant network isn’t handling the oxidative stress pretty well; your inflammation is rising. You’ll solve it with...
 
MAGNESIUM!
 
A deficiency increases directly ALL INFLAMMATORY CYTOKINES (hence soreness & fatigue) AND indirectly through increasing NF-kB ImageImage
(extra: inflammation reduces GLUT4; mgdef athletes are fucked LOL)

Nuclear Factor Kappa B is a genetic pathway that induces the activity of inflammatory cytokines,
commands to your immune system to "INFLAME EVERYTHING"; starts/RISES inflammation. ImageImage
Also, Mg INCREASES YOUR ANTIOXIDANT NETWORK

"MgD (deficiency) was accompanied by a TWO FOLD decrease in GLUTATHIONE concentration in Red Blood Cells"

Just by being MgD you have TWO FOLD less glutathione, your MASTER ANTIOXIDANT. Makes you an easy prey for inflammation = FATIGUE Image
There are more ways a MgD increases OS & poor workout recovery, but the mentioned are the main ones.

AND There are more ways high Mg boosts recovery:

-Increases GABA & reduces Glutamate
-Triggers Melatonin production
-Inhibit ACTH hormone release (this hormone-
tells your adrenals to produce cortisol, stress hormone)
-mg def. creates stress & a vicious cycle
-overactive nervous system, mucho calcio poco magnesio (calcium = excitatory) ImageImageImage
6. CRAMPS

“sorry coach i can’t continue, i just had a cramp"

SHUT UP. Just SHUT THE FUCK UP. Will you let a cramp stop you?

If you’re on this side of twitter, I know that you won’t, so, read carefully, because MAGNESIUM is vital for a smooth & perfect muscle contraction.
FLEX A MUSCLE. NOW. FLEX IT. FEEL THE CONTRACTION.

OK KEEP FLEXING IT. YOUR MUSCLE IS FLOODED NOW WITH CALCIUM.

CALCIUM IS A EXCITATORY MINERAL, IT ONLY ENTERS THE CELL FOR EXCITATORY/IMPULSIVE FUNCTIONS, LIKE A MUSCLE CONTRACTION.
Now stop flexing it. If you didn’t have a cramp? Congrats! Magnesium did it’s job effectively!
---
Magnesium helps active transporters to pump Ca out of your cell. BUT!

Low magnesium PREVENTS Ca pumps activity. This unables them to flush out calcium;
So in summary, Cramps  = TOO MUCH Ca and/or LOW Mg. (potassium is important too btw)

Also, the availability of glycogen has been shown to be related to the ability of the sarcoplasmic reticulum to release calcium. And what controls that ability? ImageImage
Magnesium. Your muscles glucose availability depends on Magnesium. This -ALSO- explains the YUGE glucose increase we saw on the point uno
7- CONCLUSIONS

You want to add MAGNESIUM in your POST and PRE WORKOUT.

We saw that MAG is needed DURING the workout (energy, cramps, lactate, glucose) and AFTER (glucose “absorption”, lactate, mitochondria, recovery)

So, how much?
I’ve found 1.5g of MAGNESIUM CHLORIDE IS THE PERFECT DOSE BOTH FOR not only for me, but for others as well.

500mg of Magnesium Chloride (MgCl) has 60-70mg of ELEMENTAL MAGNESIUM. The elemental quantity of a mineral is what you should focus on.

However...
Everyone is different. EXPERIMENT. SEE FOR YOURSELF.

Start with 1g of MgCl for BOTH the PRE and POST workout.

I’ll actualize the Mag Forms thread ASAP, since i’ve discovered new OP forms. Stay tuned

also i hate that version of myself LOL
USE TOPICAL MAGNESIUM! (epsom salts and/or mag flakes works too)

Game changer. My muscles feel "lighter" and +powerful. This "delivers" magnesium right where you want, so...

Apply it in the CORE and in the muscles you’ll work out.
Apply it in the SAME places after your match/workout.

ZEUS RECOVERY.

This from @ancientminerals is the absolute best I’ve used (im not an affiliate but i'd proudly be one 😉)
shop.enviromedica.com/ancient-minera…
MAG SOURCES Image
Other KEY nutrients for you, athlete: Cholesterol, B1, B5 (all b vitamins tbh), Vit. D, SUNLIGHT!!!!!!!!, Zinc, Copper, Sodium (from a HIGH QUALITY SOURCE like redmond salt),
Probiotics (you're eating lots of food & maybe carbs, you want a good gut to process all that), and if you’re following a very high carb diet (which i don't recommend), consume Apple Cider Vinegar.
That was all for dis thread. RT it. Spread knowledge. DOUBTS = DM

See ya
SOURCES: lmao forgot to add em yesterday momento alli

Mag & Exercise performance overview ncbi.nlm.nih.gov/pmc/articles/P…

GLUT4, Muscle & Exercise: journals.physiology.org/doi/full/10.11…

All GLUT ncbi.nlm.nih.gov/books/NBK54520…

Mag & Glucose & Lactate ncbi.nlm.nih.gov/pmc/articles/P…
(Info about lactate was retrieved from "Biochemistry" book 6th ed., by Garret & Grisham, VERY recommended book)
Mg & Mitochondria (!) nature.com/articles/srep3…

Mg & Mitochondria 2 ncbi.nlm.nih.gov/pmc/articles/P…

Mit Biogenesis Overview ncbi.nlm.nih.gov/pmc/articles/P…

Mt Biogen OvView 2 sciencedirect.com/topics/medicin…

Mitochondria are Mag stores sciencedirect.com/science/articl…
(not included) Excess glut+Ca fuck mitoch. mag stores pubmed.ncbi.nlm.nih.gov/20740499/

HIIT & Biogenesis journals.physiology.org/doi/full/10.11…

DNA Ligase ncbi.nlm.nih.gov/pmc/articles/P…

DNA Ligase Mastery deepblue.lib.umich.edu/bitstream/hand…

Exercise & Mitoch sciencedirect.com/science/articl…
1 week of Mag supp lowers soreness, inflammation & improves glucose: link.springer.com/article/10.100…

MgD: Diabetes, OS, Glucose, Insulin, Inflammation & Energy metabolism ncbi.nlm.nih.gov/pmc/articles/P…

Mg & Stress mdpi.com/2072-6643/12/1…

Mg ACTH pubmed.ncbi.nlm.nih.gov/9683002/
Lactate BDNF and Benefit ncbi.nlm.nih.gov/pmc/articles/P…

Lactate & Exercise academic.oup.com/biohorizons/ar…
Lactate & Exercise 2 ncbi.nlm.nih.gov/pmc/articles/P…

Will do a thread/article/video/podcast/IG post on lactate. Underrated for longevity. See ya.

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More from @realalejandroAD

12 Aug
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But if Homie A sleeps 9hrs…

And Homie B sleeps just 6…

Homie A will get way better results and Homie B?

Only decent results.
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MPS is how you grow muscle.

Picture your muscle as a wall and amino acids as bricks. MPS is how you add those bricks to the wall.
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Fascinating Image
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POTASSIUM DEFICIENCY SYMPTOMS:

- Poor meat digestion
- Muscle Cramps
- GERD, Acid reflux, Stomach issues
- Stiff muscles
- High Blood Pressure
- Strong Heart Palpitations
- Fatigue, specially after ☀️ exposure
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Are YOU getting enough POTASSIUM? Image
You see,

Sodium? 🧂.

Magnesium? MgCl.

Calcium? If you consume dairy you’re already getting enough.

But POTASSIUM?
Unless you’re already K-pilled and eating one 🥑 a day or adding cream of tartar to your water/smoothies/food here and there…

You’re deficient on it.
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- Get more POTASSIUM
- Kefir
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- Deep breathings before meal

Sinple Image
Didn’t include fiber because can make things worse for those with constipation.

If you have constipation, 99.9% probably that you DON’T need more fiber.
A traffic jam doesn’t gets solved by adding more cars. It gets solved by reducing the cars and evacuating them ASAP.
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Based RAW KOMBUCHA u’ll found in convenience stores

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- RAW ImageImageImage
Tastes amazing.
It surprises me that 99.999999% of probiotic drinks i’ve found here in USA have added sugar

Totally counterproductive

and soy
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26 Jul
🔮 The BENEFITS of GLYCINE (THREAD - PT I) 🔮

The SINPLEST amino acid, with GARGANTUAN benefits. But...

Glycine's benefits are beyond sleep and vivid dreams.

It's so essential for human health that loss of Glycine transporters to your brain cells...
Results in the disease "Glycine Encephalopathy",

This shows how important Glycine is for your body. Now...

What makes Glycine so imperative? Why you recover better with Glycine? Why your body uses it for 1000s of processes?

Read on to discover it.
Of all 22 amino acids, glycine is THE smallest one.

It has ONE hydrogen forming its side chain (REMEMBER THIS), rather than a Carbon as most aminos.

"Glycine" is derived from the Greek word “glykys”, meaning "sweet" - because Glycine is as sweet as glucose.

fuck sugar 👍
Read 57 tweets

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