Characterization of the emerging B.1.621 variant of interest of SARS-CoV-2 @medrxivpreprint
This one going up in Florida where case transmission is highest. It has 484 and 501 like South African and P.1 and potentially partially vaccinene escape medrxiv.org/content/10.110…
Also 681 mutation at the furin cleavage site in the more transmissible UK and delta variants, although to a histidine like UK
I don't think it has a Greek letter designation yet but based on these properties and the fact that we allowed it to take hold due to low vaccination rates in the South, (and their place in the Greek alphabet), I propose ζυ
1/n Our @TexasChildrens laboratory is rapidly accelerating a new human hookworm anemia vaccine for LMICs.
Fyi hookworm, malaria, yellow fever, dengue once common in East Texas (and in some cases returning). Here’s a hookworm map from early 1900s. Even Harris County,
1/n There have been several papers out in the last few months examining or reviewing the PEDIATRIC disease burden of Covid + the benefits of vaccination, will summarize some of the key interesting ones from 2023-24 here in this thread, in some cases also a popular article on it
1/n Well he's right about one thing, follow the money. And he will find out how we develop low-cost neglected disease vaccines for global health. I think in my 40 years of this I've made less than $3,000 from our vaccines, nothing from interviews/podcasts...but guess who has?
1/n Trump Getting DESTROYED on Truth Social Over His Vaccine Post - @MeidasTouch
To help people understand this phenomenon, it might be useful to look at each of the three major waves of COVID disinformation from 2020-2024. Will break it down… meidastouch.com/news/trump-get…
2/n V.1.0 began in 2020 when health disinformation was used to avoid stay at home orders from governors + prevent oil prices from collapsing. That’s when the Trump WH/Fox News pushed the hydroxychloroquine nonsense + Great Barrington Declaration at AIER exposedbycmd.org/2021/12/22/how…
3/n V.2.0 began with CPAC Conf in Dallas TX July 2021 pushing up against vaccine mandates (“first they’ll vaccinate then take away your guns/bibles”) + members of the House Freedom Caucus and 2 U.S. Senators falsely discredited the vaccine safety efficacy esquire.com/news-politics/…
1/n Infectious viral load in unvaccinated and vaccinated individuals infected with ancestral, Delta or Omicron SARS-CoV-2 | Nature Medicine nature.com/articles/s4159…
1/n Thought I would update where we’re at in the U.S. in terms of Covid this March 3, 2024 and make some )(hopefully constructive) comments or offer my opinion on the CDC’s revised recommendations/guidance on COVID isolation
2/n First some potentially good news in that Covid hospitalizations seem to be declining significantly. The hope is that we are heading to the other side of this JN.1 wave
3/n what comes next and when is difficult to say. It’s pretty much all JN.1 right now, and I don’t see an obvious next variant accelerating