In this one in mice, resistance exercise was found to counteract the effects of an obesogenic diet on body composition, while also being associated with improved glucose tolerance, even after exercise cessation.
- The study wanted to investigate the preventive effects of resistance exercise on body weight, gonadal fat mass, and glucose tolerance and determine whether the beneficial effects of exercise are associated with skeletal muscle strength and endurance in mice.
- Skeletal muscle strength (as measured by grip strength) and skeletal muscle endurance (as assessed by hanging time) were increased, even after exposure to an obesogenic diet for 1 week (~280 human days) after exercise discontinuation.
- Body weight, gonadal fat mass, and adipocyte size were lower, while glucose tolerance was higher in the resistance-trained mice, despite exposure to an obesogenic diet for 1 week (~280 human days) after exercise discontinuation.
- "Surprisingly, muscle strength and endurance had a significant inverse relationship with body weight, and muscle strength had a significant inverse relationship with gonadal fat weight...
"...It was confirmed that this phenomenon could be clearly distinguished depending on whether the training was performed."
- "These results suggest that resistance exercise is a potent regulator of skeletal muscle function and obesity."
- Interestingly, even though resistance exercise did improve metabolic parameters and increased muscle strength and endurance, muscle strength had a higher correlation with improved body composition and glucose tolerance than muscle endurance.
Obvious grain of salt warning: Chow intake
Resistance exercise training-induced skeletal muscle strength provides protective effects on high-fat-diet-induced metabolic stress in mice (open access)

doi.org/10.1186/s42826…

#exercise #TrainHard #GymLife #GymTime #muscle #strength #lift #GetStrong

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More from @nick_krontiris

Dec 5
This one found that the consumption of skimmed milk after exercise may reduce subsequent energy intake, such that total energy intake is not different from a low-energy placebo beverage and reduced relative to a sucrose beverage.
"The main finding was that ad-libitum energy intake 60 min after beverage ingestion was reduced following skimmed milk compared to a sucrose beverage and tended to be reduced for skimmed milk compared to the placebo beverage...
"...This meant that total energy intake (ad-libitum energy intake plus the energy provided in the post-exercise beverage) was lower following skimmed milk and placebo compared to after ingestion of the sucrose beverage...
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Dec 4
This one found distinct adiposity-related body shape phenotypes to be associated with the risk of cancer, identifying novel relationships, suggesting that cancer burden associated with adiposity and body size based on classical anthropometric traits is likely underestimated. ImageImageImage
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The hazard ratio for overall cancer risk per 1  SD increment for the overall adiposity phenotype was 1.07.
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Dec 4
In this one, both 3mg/kg and 6mg/kg doses of caffeine ingestion increased plasma catecholamine concentration and improved the average peak power output during a repeated sprint test in trained female team-sport players.
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Read 4 tweets
Dec 4
This one suggests that a higher genetic predisposition to gut microbial relative abundance is associated with greater reductions in central adiposity and body composition in response to weight-loss diet interventions, an effect that may be modified by dietary protein.
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Dec 3
This one found that Sicilian long-lived individuals have changes in circulatory fatty acids status with advancing age, characterized by a reduction in blood levels of total PUFA and trans FA with age, whereas total SFA remained unchanged throughout life. Image
- This fatty acid profle characterized by high MUFA content may indicate reduced peroxidation while maintaining membrane fluidity.
- "We suppose that the high consumption of the extra virgin olive oil (EVOO) may have infuenced this datum"
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This one found that a higher-intensity aerobic exercise is more likely to elicit greater increases in circulating exercines that are known for their neuroprotective effects.
- Findings showed that Cathepsin B was enriched in the circulation in an intensity dependent manner during aerobic exercise.
- Interestingly, skeletal muscle tissue was found expresses both message and protein of Cathepsin B (CTSB) and brain derived neurotrophic factor (BDNF), with the latter being highly expressed in glycolytic skeletal muscle fibers.
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