Meryl PharmD 💉💉 #CovidAndFungus Profile picture
ID pharmacist studying fungal infections complicating COVID • ‘Unprofessional’ • The present is viral, the future is fungal • @SIDPharm @MSG_ERC @DemsAbroadFr
13 Sep
@ashishkjha I wouldn’t be so optimistic. Immune compromised patients may not be protected even after 3 doses, especially those who can’t carry a memory of the vaccine. They have no choice but to rely on OTHERS. That’s why boosters should actually be given to those who CAN make antibodies…
@ashishkjha Circulating antibodies of the general public have to be high, they are our first line of response. It’s what will restore high levels of protection against infection/transmission, the only thing that can protect the most vulnerable from exposure. Antibodies are waning, and…
@ashishkjha … while low levels could have been sufficient to prevent infection from older variants (and onwards transmission), with Delta we are exposed to a lot more virus.
As for memory cells, they play a major role in individual protection against severe disease, but it takes a few…
Read 5 tweets
11 Sep
Natural vs vaccine induced immunity🧵
This preprint study from 🇮🇱 does NOT prove that natural immunity 'confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant'. medrxiv.org/content/10.110…
1/n
It has a major selection bias.
The sample of participants doesn't seem to be representative of the 🇮🇱 pop. The event rate in the study is much lower than that of the baseline pop in 🇮🇱  where > 1,200 infections per 100K were reported among the unvaxxed at the time.
2/n
Participants in this study doesn’t appear to be randomly selected. There was little adjustment and confidence intervals are too large. ➡️ we can’t rely on the results.
Besides it’s a RETROSPECTIVE observational study ➡️ a lot of infections can be missed
3/n
Read 12 tweets
2 Sep
#Thread🧵
I see a lot of misinformation about immunity conferred by prior infection vs vaccination, most notably because of a recent preprint study from Israel. But this study does NOT prove that natural immunity 'confers longer lasting & stronger protection’ against Delta
1/n
The level of protection from infection can vary a lot. Besides, ONE outlying study with lots of caveats CANNOT negate all other data we have so far! There are well conducted studies that demonstrated the exact opposite, including this one 👇
2/n
First of all, immunity through infection - also referred to as natural immunity - means you have to get infected to have that protection !
Letting people get infected has no public health benefit 🤷‍♀️
3/n
Read 12 tweets