Thread Reader helps you read and share Twitter threads easily!
I'm @ThreadReaderApp a Twitter bot here to help you read threads more easily. To trigger me, you just have to reply to (or quote) any tweet of the thread you want to unroll and mention me with the "unroll" keyword and I'll send you a link back on Twitter 😀
— Thread Reader App (@threadreaderapp) November 25, 2017
X thread is series of posts by the same author connected with a line!
From any post in the thread, mention us with a keyword "unroll"
@threadreaderapp unroll
Follow @ThreadReaderApp to mention us easily!
Practice here first or read more on our help page!
Recent
You are taking magnesium. It may be the wrong form for your symptoms.
The form determines bioavailability, tissue destination, and clinical effect. Magnesium oxide is what most drugstores stock. It's also the least useful form for Long COVID symptoms.
The form determines bioavailability, tissue destination, and clinical effect. Magnesium oxide is what most drugstores stock. It's also the least useful form for Long COVID symptoms.
2/8 Magnesium oxide has poor bioavailability.
Most of it reaches the colon, draws water in, and produces a laxative effect.
If you're taking oxide for sleep, fatigue, or brain fog, it isn't delivering meaningful amounts to the tissues where those symptoms originate.
Most of it reaches the colon, draws water in, and produces a laxative effect.
If you're taking oxide for sleep, fatigue, or brain fog, it isn't delivering meaningful amounts to the tissues where those symptoms originate.
3/8 Magnesium glycinate binds magnesium to glycine, an inhibitory amino acid.
Glycine supports calming neurotransmitter activity. If your target is sleep disruption, racing thoughts at bedtime, or nighttime sympathetic surges, glycinate is the form to ask about.
Glycine supports calming neurotransmitter activity. If your target is sleep disruption, racing thoughts at bedtime, or nighttime sympathetic surges, glycinate is the form to ask about.
Everyone thinks gray hair is the result of genetics and aging.
It's not.
It's your body breaking down its own tissues to survive stress.
Here's the real culprit (and how to reverse it): 🧵
It's not.
It's your body breaking down its own tissues to survive stress.
Here's the real culprit (and how to reverse it): 🧵
Aging and genetics play a role in gray hair.
But lifestyle factors can significantly affect how early gray hair appears.
This is where epigenetics comes in.
Your habits influence how your genes express themselves.
But lifestyle factors can significantly affect how early gray hair appears.
This is where epigenetics comes in.
Your habits influence how your genes express themselves.
There are two primary contributors to premature graying:
1/ Decreased melanin production
2/ Increased oxidative stress within the hair follicle
Let’s examine each one…
1/ Decreased melanin production
2/ Increased oxidative stress within the hair follicle
Let’s examine each one…
Thiamine (vitamin B1) megadosing improved survival by over 8X in sepsis, a condition that kills ~20% of all people, in a recent study.
(🧵1/7)
(🧵1/7)
This study came out in 2024, looking at 2 different randomized clinical trials of thiamine (B1) usage in sepsis.
Sepsis is when there is bacterial leakage into the bloodstream in large amounts.
This causes massive inflammation that ultimately causes organ failure and often death.
Sepsis is when there is bacterial leakage into the bloodstream in large amounts.
This causes massive inflammation that ultimately causes organ failure and often death.
This was a post hoc analysis - essentially they looked at two prior trials' data and then analyzed it for different endpoints.
The first two studies were mainly concerned about the effects of B1 on preserving kidney function.
This one was looking at survival overall.
The first two studies were mainly concerned about the effects of B1 on preserving kidney function.
This one was looking at survival overall.
🧵As I watch US podcasts on the internet about #Russia’s war against #Ukraine what I see increasingly defies reason. Academics like Mearsheimer or Sachs de facto repeat Russian talking points. For years now retired US colonels continue to declare #Ukraine’s imminent end, etc. 1/6
Most of the people who pontificate on Russia have never been outside of Moscow/Petersburg, if that. They don’t speak a word of Russian, nor Ukrainian. Instead, IR theory and, frankly, chutzpah substitute for country expertise as they boldly predict Ukraine’s imminent demise. 2/6
War is not a professor’s seminar on his/her pet IR theory. Service in the US military doesn’t give one genuine expertise on Eurasia. What I find most jarring is the apparent glee with which they claim their views to be strategic gospel. Zero humility. Zero self-reflection. 3/6
Is ACP International Secretary Christopher Helali LYING about his time in Syria “fighting ISIS” alongside the YPG?
BY HIS OWN ADMISSION, Helali
• Spent only WEEKS on the frontline — not MONTHS
• NEVER entered the city of Raqqa
• Took part in ZERO offensive operations
BY HIS OWN ADMISSION, Helali
• Spent only WEEKS on the frontline — not MONTHS
• NEVER entered the city of Raqqa
• Took part in ZERO offensive operations
Helali boasts he spent “nine months in total” in Syria, obfuscating his actual time spent on the front — 2 months — before ”We got pulled off the front line, so we didn't enter the city at that point...we got pulled from the front...I never fought in the city itself.”
Despite claiming a role in the Battle of Raqqa, Helali was only “40 to 50 km” outside the city proper - not the urban battle for Raqqa itself.
His unit was placed at village checkpoints with as few as six people.
Much of the "combat" he describes is being shot at or hiding.
His unit was placed at village checkpoints with as few as six people.
Much of the "combat" he describes is being shot at or hiding.
@hannahspierMD @dysclinic 1/Ok, perhaps your comment wasn’t as deliberately offensive as it appeared.
I think what you need to understand is that patients with ME/CFS, Long Covid & other PAIS are severely organically and physically unwell. This has been proven in science irrevocably. In the same way we
I think what you need to understand is that patients with ME/CFS, Long Covid & other PAIS are severely organically and physically unwell. This has been proven in science irrevocably. In the same way we
@hannahspierMD @dysclinic 2/we know irrevocably that the Earth is round and not flat.
Now imagine you suffer from one of these illnesses where you have neuroimmune pathology, mitochondrial and vascular damage, multi-organ damage and mitochondrial damage resulting in impaired metabolic recovery to any 2/
Now imagine you suffer from one of these illnesses where you have neuroimmune pathology, mitochondrial and vascular damage, multi-organ damage and mitochondrial damage resulting in impaired metabolic recovery to any 2/
@hannahspierMD @dysclinic 3/physical or cognitive exertion or task. Your body is broken and the effort of even performing ADLs can render you bedridden for weeks. Now imagine developing one of these illnesses, having your previously normal life completely ripped away from you. You are sick, you r scared
A scientist was hired by a chemical company to study its weedkiller. He found it was castrating and feminizing frogs. So the company stopped studying the chemical and started studying him. This is the documented story of atrazine. 🧵
Tyrone Hayes, a Berkeley biologist, found atrazine scrambled frog sexual development. Genetically male frogs were chemically castrated. Some were so feminized they mated with other males and laid viable eggs. Published in PNAS.
Internal records later unsealed in litigation showed the company's PR team drew up goals. Goal number one: "discredit Hayes." Notes described investigating his wife, tracking his talks, and keeping a roster of ~130 supposedly independent experts to deploy on demand.
This is one of $NVDA’s latest investments.
Almost nobody is covering it. These are exactly the kind of names you want to find first.
Here it is:
Almost nobody is covering it. These are exactly the kind of names you want to find first.
Here it is:
🚨 IMPORTANT:
We're a team of 8 with one goal: to help you spot truly great stocks at the earliest stage.
Turn on notifications and follow us. It is crucial not to miss the alerts.
If you don’t follow us, you might regret it later.
We're a team of 8 with one goal: to help you spot truly great stocks at the earliest stage.
Turn on notifications and follow us. It is crucial not to miss the alerts.
If you don’t follow us, you might regret it later.
GENB Generate Biomedicines.
Clinical-stage biotech using generative AI to design new proteins and therapeutics from scratch.
They call it Generative Biology. Founded 2018 by Flagship Pioneering. HQ Somerville, MA.
This is what AI in drug discovery actually looks like.
Clinical-stage biotech using generative AI to design new proteins and therapeutics from scratch.
They call it Generative Biology. Founded 2018 by Flagship Pioneering. HQ Somerville, MA.
This is what AI in drug discovery actually looks like.
Does eating late at night make you fat?
Should you eat breakfast within 30 minutes of waking up?
Is there a best time to eat your carbs?
Everyone has an opinion on meal timing.
Here is what the evidence actually says.
Thread:
Should you eat breakfast within 30 minutes of waking up?
Is there a best time to eat your carbs?
Everyone has an opinion on meal timing.
Here is what the evidence actually says.
Thread:
The short answer:
The short answer is that meal timing matters much less than most people think.
The most important variable in fat loss is not when you eat.
It is how much you eat relative to how much your body burns.
A calorie eaten at 7am and a calorie eaten at 10pm are processed by your body in essentially the same way.
Your body does not have a clock that converts food into fat after a certain hour.
It has a system that stores excess energy as fat regardless of what time that excess arrived.
Total calories consumed versus total calories burned.
That is the variable that determines fat loss.
Not the time on the clock when the food was eaten.
The short answer is that meal timing matters much less than most people think.
The most important variable in fat loss is not when you eat.
It is how much you eat relative to how much your body burns.
A calorie eaten at 7am and a calorie eaten at 10pm are processed by your body in essentially the same way.
Your body does not have a clock that converts food into fat after a certain hour.
It has a system that stores excess energy as fat regardless of what time that excess arrived.
Total calories consumed versus total calories burned.
That is the variable that determines fat loss.
Not the time on the clock when the food was eaten.
So why do people gain weight eating late:
If meal timing does not matter why do so many people gain weight from eating late at night?
The answer is not the timing.
It is what eating late represents in most people's daily pattern.
Late night eating is almost always eating outside of your planned meals.
It is impulsive. Emotional. Driven by boredom or habit rather than genuine hunger.
And the foods eaten late at night are almost never the foods that support fat loss.
Garri. Bread. Biscuits. Leftovers. Whatever is in the kitchen.
It is not the 10pm timing that causes fat gain.
It is the extra unplanned calories consumed at 10pm on top of everything already eaten during the day.
Remove the late night eating and most people reduce their daily calorie intake by 300 to 500 calories without changing anything else.
That reduction creates a deficit.
The deficit produces fat loss.
The timing was never the issue.
The extra calories were.
If meal timing does not matter why do so many people gain weight from eating late at night?
The answer is not the timing.
It is what eating late represents in most people's daily pattern.
Late night eating is almost always eating outside of your planned meals.
It is impulsive. Emotional. Driven by boredom or habit rather than genuine hunger.
And the foods eaten late at night are almost never the foods that support fat loss.
Garri. Bread. Biscuits. Leftovers. Whatever is in the kitchen.
It is not the 10pm timing that causes fat gain.
It is the extra unplanned calories consumed at 10pm on top of everything already eaten during the day.
Remove the late night eating and most people reduce their daily calorie intake by 300 to 500 calories without changing anything else.
That reduction creates a deficit.
The deficit produces fat loss.
The timing was never the issue.
The extra calories were.
Almost one year after SARS2 infection, children with Long COVID showed measurable changes in the tiny blood vessels of the retina.
Wider arterioles.
Wider venules.
A shifted arteriole-to-venule ratio.
This was not just a symptom survey.
It was an objective microvascular signal🧵
Wider arterioles.
Wider venules.
A shifted arteriole-to-venule ratio.
This was not just a symptom survey.
It was an objective microvascular signal🧵
The authors looked at retinal blood vessels in the eye - because the retina offers a non-invasive window into the body’s microcirculation.
And this was not just a few weeks after infection.
The first examination happened roughly 44-50 weeks after SARS2 infection.
So, basically, around one year later.
The first examination happened roughly 44-50 weeks after SARS2 infection.
So, basically, around one year later.
If I had 12 months & wanted to make $100,000 online at 35 years old, I'd copy this unknown solopreneur:
@heyizmadz turned 5000 X followers into 6 figures.
She only needed 55 clients to do it.
I interviewed her for my private mastermind.
Here's exactly how she did it (and you can too):
She only needed 55 clients to do it.
I interviewed her for my private mastermind.
Here's exactly how she did it (and you can too):
@heyizmadz 1. Stop being a little b*tch.
Madz is 23.
Comes from a 3rd world country
Studied marketing in college and dropped out.
She told herself an empowering story and made it happen.
Making money online is 90% mindset.
Madz is 23.
Comes from a 3rd world country
Studied marketing in college and dropped out.
She told herself an empowering story and made it happen.
Making money online is 90% mindset.
1/10 🧵
In From Divine Timemaker to Divine Watchmaker, R. T. Mullins argues that the classical doctrine of divine timelessness faces serious philosophical and theological difficulties. The book defends a robust form of divine temporality instead.
In From Divine Timemaker to Divine Watchmaker, R. T. Mullins argues that the classical doctrine of divine timelessness faces serious philosophical and theological difficulties. The book defends a robust form of divine temporality instead.
2/10 Author traces how many classical theologians identified perfection with timelessness, immutability, and impassibility. He questions whether these commitments arise from Scripture itself or from broader metaphysical assumptions inherited from antiquity.
3/10
A central concern is agency. If God is wholly outside succession, how can God genuinely act, respond, create, judge, or interact with temporal creatures? Mullins argues that timelessness struggles to make sense of divine action.
A central concern is agency. If God is wholly outside succession, how can God genuinely act, respond, create, judge, or interact with temporal creatures? Mullins argues that timelessness struggles to make sense of divine action.
