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Time for a big systems advice thread!
In distributed systems there's no magic "push everything to prod at once" button. Every service gets pushed independently and nodes within a service get updated incrementally. If you mess up forwards/backwards compatibility you can fail irrecoverably.
So how to avoid this?
1/5: Decouple data and code changes. Never push out a release that changes how data is stored at the same time as the code that uses this new data. If there's a bug and you need to roll back to the old version of your code it won't be able to handle the new data in the new format. Instead push out a release that first changes the data in a way that’s compatible with both the old and new code (e.g., optional fields etc), when that’s stable push out the new code that uses it, then when that’s stable you can change the data to remove backwards compatibility. This is known as a “migration” in the database world and yes it’s annoying, but yes you need to do it.
In distributed systems there's no magic "push everything to prod at once" button. Every service gets pushed independently and nodes within a service get updated incrementally. If you mess up forwards/backwards compatibility you can fail irrecoverably.
So how to avoid this?
1/5: Decouple data and code changes. Never push out a release that changes how data is stored at the same time as the code that uses this new data. If there's a bug and you need to roll back to the old version of your code it won't be able to handle the new data in the new format. Instead push out a release that first changes the data in a way that’s compatible with both the old and new code (e.g., optional fields etc), when that’s stable push out the new code that uses it, then when that’s stable you can change the data to remove backwards compatibility. This is known as a “migration” in the database world and yes it’s annoying, but yes you need to do it.
2/5: Don’t change two services at once. If service A talks to service B, you can’t just add a new API to both of them and push them out. What if someone pushes A but not B? What if there’s a bug in B that needs to be rolled back? Just like with data changes, API changes need to be made in a forwards and backwards compatible way. Engineers forget to do this all the time.
3/5: Only allow one version “step” to exist in prod at any time. It’s common to have most of your nodes at version 5 but a few are still at version 4 because they haven’t finished migrating. Never ever allow someone to push to version 6 while version 4 is still running. Otherwise it’s too hard for engineers to reason about which version is “stable” when making multi-step migrations. You need monitoring and alerting for this plus protections agains corner cases, e.g., if a node was offline and then came back online after missing a code push.
1/ During measles outbreaks, vitamin A gets mentioned for a reason.
But recommending cod liver oil for prevention crosses a critical line—from evidence-based care to biochemical risk.
Here’s what actually happens in the liver. 👇
But recommending cod liver oil for prevention crosses a critical line—from evidence-based care to biochemical risk.
Here’s what actually happens in the liver. 👇
2/ Vitamin A is not just a nutrient.
It’s a fat-soluble signaling molecule stored in the liver.
Unlike water-soluble vitamins, excess isn’t easily excreted—it accumulates.
That’s where the problem begins.
It’s a fat-soluble signaling molecule stored in the liver.
Unlike water-soluble vitamins, excess isn’t easily excreted—it accumulates.
That’s where the problem begins.
3/ Under normal conditions:
Vitamin A is stored in hepatic stellate cells as retinyl esters.
Released slowly, bound to proteins, tightly regulated.
But this system has limits.
Vitamin A is stored in hepatic stellate cells as retinyl esters.
Released slowly, bound to proteins, tightly regulated.
But this system has limits.
1/8) We are excited that our paper has been published with lead author @maxinewaters250 and @dbkell
In this study, we investigate Post-Vaccination/Post-Infection Syndrome (PV/PIS) and its underlying biology.
🔗 frontiersin.org/journals/cellu…
In this study, we investigate Post-Vaccination/Post-Infection Syndrome (PV/PIS) and its underlying biology.
🔗 frontiersin.org/journals/cellu…
2/8) A key challenge:
Patients present with persistent symptoms after vaccination or infection, often overlapping with Long COVID.
Distinguishing these clinically is difficult; and biology is still poorly understood.
Patients present with persistent symptoms after vaccination or infection, often overlapping with Long COVID.
Distinguishing these clinically is difficult; and biology is still poorly understood.
3/8) We approached this differently.
Instead of looking only at soluble plasma proteins, we analysed proteins trapped inside the insoluble fraction.
This is where important pathology is often hidden.
Instead of looking only at soluble plasma proteins, we analysed proteins trapped inside the insoluble fraction.
This is where important pathology is often hidden.
Testosterone is what makes men alive. It affects how you think, Fight and F*ck.
Here are 8 best foods to boost it:
Here are 8 best foods to boost it:
I Have Seen My Affliction! 🧵
Jeremiah wrote Lamentations about a nation who had turned their backs on God’s Word and were living in sin, while surrounded by false prophets telling them all was well.
Jeremiah wrote Lamentations about a nation who had turned their backs on God’s Word and were living in sin, while surrounded by false prophets telling them all was well.
But Jeremiah had also seen his own affliction brought about by his sin.
Jeremiah said this in Lamentations 3:1: I am the man that hath seen affliction by the rod of His wrath.
Jeremiah said this in Lamentations 3:1: I am the man that hath seen affliction by the rod of His wrath.
Instead of telling the truth about what had led these people into captivity—their own sinfulness. These false prophets prophesied lies to the people.
This is extremely concerning!
A new study found that the sweetener used in millions of Americans' daily snacks can damage human brain cells within hours of a single serving.
The FDA approved it decades ago, but the new data is worrying: (1/15)
A new study found that the sweetener used in millions of Americans' daily snacks can damage human brain cells within hours of a single serving.
The FDA approved it decades ago, but the new data is worrying: (1/15)
Researchers at the University of Colorado Boulder tested brain blood vessel cells against the amount of erythritol found in one sweetened drink.
Within 3 hours, the cells showed measurable, significant damage, after just one drink.
But what even is erythritol?
Within 3 hours, the cells showed measurable, significant damage, after just one drink.
But what even is erythritol?
Erythritol is a sugar alcohol used as a zero-calorie sweetener.
It tastes like sugar, has no glycemic impact, and the FDA approved it as safe. That's why it became the go-to ingredient in keto and sugar-free products.
If you avoid sugar, you are likely eating this regularly.
It tastes like sugar, has no glycemic impact, and the FDA approved it as safe. That's why it became the go-to ingredient in keto and sugar-free products.
If you avoid sugar, you are likely eating this regularly.
Millwall | Attacking Set Piece analysis
This season Millwall have been one of the most prolific set piece teams in England
22 goals In 41 games | 39% of total team league goals
In this thread I’ll be analyzing their
-Corners
-Wide Free Kicks
-Throw ins
@tacticlipfutbol
This season Millwall have been one of the most prolific set piece teams in England
22 goals In 41 games | 39% of total team league goals
In this thread I’ll be analyzing their
-Corners
-Wide Free Kicks
-Throw ins
@tacticlipfutbol
ATTACKING DATA
Millwall’s attacking output from set pieces as of the 9th April 2026
As we can see Millwall’s set piece form has been crucial in their promotion challenge
Millwall’s attacking output from set pieces as of the 9th April 2026
As we can see Millwall’s set piece form has been crucial in their promotion challenge
XG DATA - by Opta Analyst
Millwall’s XG data: they’re over performing by 4 goals
They’ve been very proficient at creating chances - 4.61 per game - indicating strong first contact success
They rank in the top 5 across all key set piece metrics
Millwall’s XG data: they’re over performing by 4 goals
They’ve been very proficient at creating chances - 4.61 per game - indicating strong first contact success
They rank in the top 5 across all key set piece metrics
Traditional directors flimmaxxxing using Seedance 2.0 on Higgsfield.
Watch “Zephyr” FULL Ep.1 – this is what happens when filmmakers face ZERO gatekeeping.
With Unlimited Seedance 2.0 now LIVE everywhere for anyone with up to 70% OFF* - YOU can build your next viral AI movie.
2 minute intro got MILLIONS in a day.
Now see how full Zephyr takes over your feed.
Dir. by ILYA KARCHIN & the team.
Zephyr (2026)
Watch “Zephyr” FULL Ep.1 – this is what happens when filmmakers face ZERO gatekeeping.
With Unlimited Seedance 2.0 now LIVE everywhere for anyone with up to 70% OFF* - YOU can build your next viral AI movie.
2 minute intro got MILLIONS in a day.
Now see how full Zephyr takes over your feed.
Dir. by ILYA KARCHIN & the team.
Zephyr (2026)
*7-days Unlimited - from the moment of purchase
Free Generations are for all Start/Basic+ plans
Seedance 2.0 is accessible for Plus+ plans
Seedance 2.0 Fast is accessible for all plans
Free Generations are for all Start/Basic+ plans
Seedance 2.0 is accessible for Plus+ plans
Seedance 2.0 Fast is accessible for all plans
OST:
ZEPHYR - Lethal Dose
ZEPHYR - Loaded
ZEPHYR - Slash
Watch Zephyr Ep.1 NOW:
higgsfield.ai/original-serie…
ZEPHYR - Lethal Dose
ZEPHYR - Loaded
ZEPHYR - Slash
Watch Zephyr Ep.1 NOW:
higgsfield.ai/original-serie…
🚨 BREAKING: Claude can now grow your TikTok like a $5,000/mo agency. For free.
Here are 5 prompts for explosive TikTok reach:
Here are 5 prompts for explosive TikTok reach:
Act as a TikTok algorithm expert. I'm in [niche]. Give me 20 video ideas engineered to hit the FYP. Include hook, format, and ideal length for each.
Write a 60-second TikTok script for [topic] that stops the scroll in the first 2 seconds. Include pattern interrupts, pacing notes, and a share-triggering ending.
Hungary is the fight for the future of Europe. The election promises a change of power, but the Orbán regime and its supporters in the Kremlin will not go quietly. The EU cannot stand idly by. My op-ed in @zeitonline: zeit.de/politik/auslan…
With an aggressive Russia and a complicit America, what will Europe do to protect its values and interests? Is it willing to take on the role of leader of the free world, or will it stand by and watch events unfold, even as they move from its doorstep to squarely at home?
The war in Ukraine has forced European politicians to think pragmatically. For all my emphasis on values, this is good; if moral conviction isn't enough to get Europe’s leaders to intervene on behalf of freedom, but imminent threat of war & democratic collapse will, so be it.
🔬Study shows SARS-CoV-2 causes direct damage to heart cell mitochondria - even months after recovery - helping potentially explain Long COVID heart symptoms like chest pain, palpitations & fatigue.
Let’s break it down 🧵
Let’s break it down 🧵
Researchers studied 5 people who had COVID-19 weeks or months earlier. They all had new or unusual heart problems, like chest pain, irregular heartbeat, or even cardiac arrest.
Each patient had a heart biopsy (a sample of heart tissue examined under a microscope).
Each patient had a heart biopsy (a sample of heart tissue examined under a microscope).
All 5 patients were diagnosed with myocarditis - inflammation and injury in heart muscle.
But interestingly, it wasn’t typical myocarditis with large immune cell infiltration. Inflammation was mild.
The key problem? Structural damage inside the heart muscle cells.
But interestingly, it wasn’t typical myocarditis with large immune cell infiltration. Inflammation was mild.
The key problem? Structural damage inside the heart muscle cells.
"I have never had any knowledge of Epstein abuse of his victims. I was never involved in any capacity." - Melania Trump...
A timeline of connections, encounters, pictures, associates. Twenty sourced images and quotes along the twists and turns of Melania, the Donald, Jeffrey, and Ghislaine.
It is 1986. A girl from Slovenia works as a model. She is young. She runs the circuit, the one that moves Eastern European girls westward, through Milan, through Paris, toward New York.
At the same time, Jean-Luc Brunel runs an international modeling operation called Karin Models. He sources teenagers from all over the world. He is a serial rapist. He preys on poor girls and traffics them. In 1988, he is the subject of a seven-month invetigation reported on 60 minutes. He continues operating.
A man named Paolo Zampolli scouts the girl and brings her to America in 1996. She does photoshoots. Rent is deducted from her paychecks for a shared apartment. The arrangement is simple. Cover the rent or go home.
In 1998, Zampolli throws a party. A big one. The kind modeling agents throw. He brings the Slovenian girl out to meet the VIP. The VIP is Donald Trump. Trump is on a date with a Norwegian heiress named Celina Midelfart. Epstein dated Midelfart first and "gave" her to Trump. There is a photograph of Midelfart with Trump and his daughter Ivanka. The two women look remarkably alike. In Epstein's birthday book, someone writes a giant novelty check for $22,500 — the price of a "fully depreciated" model. It is a joke. Everyone laughs.
gettyimages.com/detail/news-ph…
pbs.org/newshour/natio…
A timeline of connections, encounters, pictures, associates. Twenty sourced images and quotes along the twists and turns of Melania, the Donald, Jeffrey, and Ghislaine.
It is 1986. A girl from Slovenia works as a model. She is young. She runs the circuit, the one that moves Eastern European girls westward, through Milan, through Paris, toward New York.
At the same time, Jean-Luc Brunel runs an international modeling operation called Karin Models. He sources teenagers from all over the world. He is a serial rapist. He preys on poor girls and traffics them. In 1988, he is the subject of a seven-month invetigation reported on 60 minutes. He continues operating.
A man named Paolo Zampolli scouts the girl and brings her to America in 1996. She does photoshoots. Rent is deducted from her paychecks for a shared apartment. The arrangement is simple. Cover the rent or go home.
In 1998, Zampolli throws a party. A big one. The kind modeling agents throw. He brings the Slovenian girl out to meet the VIP. The VIP is Donald Trump. Trump is on a date with a Norwegian heiress named Celina Midelfart. Epstein dated Midelfart first and "gave" her to Trump. There is a photograph of Midelfart with Trump and his daughter Ivanka. The two women look remarkably alike. In Epstein's birthday book, someone writes a giant novelty check for $22,500 — the price of a "fully depreciated" model. It is a joke. Everyone laughs.
gettyimages.com/detail/news-ph…
pbs.org/newshour/natio…
Also in 1998, Epstein and Brunel are documented on their first flights together on the Lolita Express.
A few weeks after the party, Trump and the Slovenian girl are dating. Her name is Melania Knauss.
Zampolli and Epstein partner to bid on Elite Model Management. But that comes later.
In February 1999, Trump, Melania, and Epstein attend the Victoria's Secret Fashion Show together. On June 8, Trump finalizes his divorce from Marla Maples. That same year, he founds Trump Model Management.
He now manages Melania Knauss.
youtube.com/watch?v=quKq6W…
A few weeks after the party, Trump and the Slovenian girl are dating. Her name is Melania Knauss.
Zampolli and Epstein partner to bid on Elite Model Management. But that comes later.
In February 1999, Trump, Melania, and Epstein attend the Victoria's Secret Fashion Show together. On June 8, Trump finalizes his divorce from Marla Maples. That same year, he founds Trump Model Management.
He now manages Melania Knauss.
youtube.com/watch?v=quKq6W…
In 2000, he hires twenty-year-old Paris Hilton. She is his daughter's friend. He says on camera that when he first met her she was twelve, and when the little girl entered the room, he "said 'who the hell is that!?'"
In January 2000, a photographer named Antoine Verglas shoots Melania nude for GQ. Verglas is a close Epstein associate. The files show it plainly. Exchanges of photos. Scheduling of shoots. Visa arrangements. Verglas helps secure a visa for Karyna, who Epstein will name the primary benificiary for his estate. Epstein helps Verglas's son's career. Favors go back and forth.
In February, Verglas shoots Melania for Sports Illustrated's swimsuit issue. In June, for Maximum Golf.
x.com/jonathanchait/…
spd.org/flashback-frid…
In January 2000, a photographer named Antoine Verglas shoots Melania nude for GQ. Verglas is a close Epstein associate. The files show it plainly. Exchanges of photos. Scheduling of shoots. Visa arrangements. Verglas helps secure a visa for Karyna, who Epstein will name the primary benificiary for his estate. Epstein helps Verglas's son's career. Favors go back and forth.
In February, Verglas shoots Melania for Sports Illustrated's swimsuit issue. In June, for Maximum Golf.
x.com/jonathanchait/…
spd.org/flashback-frid…
