2) The study highlights that in the 3 months prior to June 2023, 8.9% of Canadian adults reported being infected, and in the six months prior, the proportion was 13.7%. It is noted that older adults and males were less likely to report multiple infections.
#SARS_CoV_2IsAirborne cureus.com/articles/24332โฆ 2) This study analyzes COVID-19 case data from January 2020 to May 2023 in Hiroshima Prefecture, Japan and compares it to national data. Meteorological factors are also examined.
medrxiv.org/content/10.110โฆ 2) The study used an FDA-approved assay to measure levels of the brain injury biomarkers GFAP and UCH-L1 in COVID-19 patients and controls.
UCH-L1, also known as Ubiquitin C-terminal hydrolase L1, is a protein that is primarily found in neurons in the brain.
medrxiv.org/content/10.110โฆ 2) The study analyzed COVID-19 transmission dynamics using an infection network constructed from epidemiological data in South Korea from January 2020 to July 2021. This network maps the infector-infectee relationships.
(๐ ๐ณ๐ฆ๐ท๐ช๐ฆ๐ธ ๐ฐ๐ง 3 ๐ด๐ต๐ถ๐ฅ๐ช๐ฆ๐ด ๐ฐ๐ฏ ๐ต๐ฉ๐ช๐ด ๐ต๐ฐ๐ฑ๐ช๐ค) 2) Mannose Binding Lectins (MBLS), which can be found in many vegetables as leeks, are proteins that play a crucial role in our innate immune system. They recognize and bind to pathogens, including coronaviruses like SARS-CoV-1 and SARS-CoV-2.
Spatial distribution of the Covid-19 cell.com/heliyon/fullteโฆ 2) The study used a Bayesian spatiotemporal regression model to identify risk factors associated with Covid-19 infection rates in neighborhoods of Cรบcuta, Colombia between 2020-2022.
Over 65,000 Covid cases were reported, with rates varying significantly between neighborhoods
sciencedirect.com/science/articlโฆ 2) SARS-CoV-2 entry into host cells requires interactions between the viral spike protein and the ACE2 receptor on the cell surface. This process depends on cholesterol-rich membrane domains in the plasma membrane.
frontiersin.org/articles/10.33โฆ 2) Zinc is an essential micronutrient that plays an important role in immune function and cell signaling. It is required for the normal development and functioning of immune cells like neutrophils, B cells, NK cells, and T cells.
"๐๐ช๐ฉ๐๐ฉ๐๐ค๐ฃ๐๐ก ๐๐ฎ๐ฃ๐๐ข๐๐๐จ ๐ค๐ ๐๐ผ๐๐-๐พ๐ค๐-2: ๐๐ข๐ฅ๐๐๐ฉ ๐ค๐ฃ ๐๐ช๐ฉ๐ช๐ง๐ ๐พ๐๐๐๐ฟ-19 ๐ซ๐๐๐๐๐ฃ๐ ๐จ๐ฉ๐ง๐๐ฉ๐๐๐๐๐จ" cell.com/heliyon/fullteโฆ 2) SARS-CoV-2 is prone to mutations due to its RNA virus nature. Mutations allow the virus to evolve and gain advantages like increased transmissibility.
Variants of concern (VOCs) like Alpha, Beta, Gamma, Delta, and Omicron have mutations that enhance binding to the ACE2 ...
"The effect of Citrus reticulata peel extract containing hesperidin on inhibition of SARS-CoV-2 infection" biorxiv.org/content/10.110โฆ 2) In this very interesting study, researchers investigated the anti-SARS-CoV-2 effects of hesperidin (HSD), hesperetin (HST), and orange peel extract containing these flavonoids.ย
HSD and HST are the major bioactive compounds in orange peel.
"๐ง๐๐ฅ๐ / ๐ฆ๐๐ฅ๐ฆ-๐๐ข๐ฉ-2"
๐๐ฐ ๐ฎ๐บ ๐ง๐ณ๐ช๐ฆ๐ฏ๐ฅ๐ด @DavidJoffe64 @siamosolocani 2) For those interested in the innate immune system and receptors other than ACE2, two fascinating studies carried out by Italian teams.
But first, a brief overview of TLRs.
๐๐ค๐ก๐ก-๐ก๐๐ ๐ ๐ง๐๐๐๐ฅ๐ฉ๐ค๐ง๐จ (TLRs) are protein receptors found on the surface of immune cells.
๐๐ฉ๐ข๐ฏ๐ฌ๐ด ๐ต๐ฐ @jlerollblues ๐ง๐ฐ๐ณ ๐ต๐ฉ๐ช๐ด ๐ด๐ต๐ถ๐ฅ๐บ ๐ mdpi.com/2076-2607/11/5โฆ 2) An outbreak of highly pathogenic avian influenza H5N1 virus occurred in a mixed-species farm in Italy, infecting and killing laying hens. Geese, ducks and pigs in the same farm remained healthy.
While viral RNA was not detected in nasal swabs from pigs, robust seroconversion,
๐๐ฐ๐ญ๐จ๐ช ๐ข๐ฑ๐ฑ๐ข๐ณ๐ข๐ต๐ถ๐ด, ๐ต๐ฉ๐ฆ "๐ธ๐ข๐ณ๐ฆ๐ฉ๐ฐ๐ถ๐ด๐ฆ ๐ฐ๐ง ๐ค๐ฆ๐ญ๐ญ๐ด" ๐ธ๐ฉ๐ฆ๐ณ๐ฆ ๐ฑ๐ณ๐ฐ๐ต๐ฆ๐ช๐ฏ๐ด ๐ข๐ณ๐ฆ ๐ฎ๐ฐ๐ฅ๐ช๐ง๐ช๐ฆ๐ฅ ๐ข๐ฏ๐ฅ ๐ฑ๐ข๐ค๐ฌ๐ข๐จ๐ฆ๐ฅ. 2) I never managed to hide my fascination ๐ค for this extraordinary apparatus, which is at the heart of cells, and which plays a major role in the replication of viruses.
biorxiv.org/content/10.110โฆ 2) The study compared metabolic profiles, including measures of oxidative stress, in lymphocytes from healthy controls, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) patients, and Long COVID (LC) patients.
What are plasma omega-3 fatty acids ? ๐ค nature.com/articles/s4159โฆ 2) ๐๐ก๐๐จ๐ข๐ ๐ค๐ข๐๐๐-3 ๐๐๐ฉ๐ฉ๐ฎ ๐๐๐๐๐จ are a type of fat found in the blood. They are important for overall health and are derived from the consumption of foods rich in omega-3 fatty acids, such as fatty fish, nuts, and seeds.
What is "Complement system" ?
What is "IgA nephropaty ? ๐ค sciencedirect.com/science/articlโฆ 2) ๐พ๐ค๐ข๐ฅ๐ก๐๐ข๐๐ฃ๐ฉ ๐จ๐ฎ๐จ๐ฉ๐๐ข is part of the innate immune system and plays an important role in the body's response. It is a group of proteins found in blood plasma that helps eliminate pathogens and damaged cells and acts as a bridge between innate and adaptive immunity.
May 6 โข 7 tweets โข 3 min read
๐พ๐๐๐๐ฟ-19 : ๐ก๐ค๐จ๐จ ๐ค๐ ๐๐จ๐จ๐๐ฃ๐ฉ๐๐๐ก ๐๐พ๐1+ ๐ฅ๐ง๐ค๐๐๐ฃ๐๐ฉ๐ค๐ง ๐-๐๐๐ก๐ก๐จ ๐๐ฃ๐ ๐ฉ๐๐๐๐ง ๐๐๐ฅ๐๐๐๐ฉ๐ฎ ๐ฉ๐ค ๐จ๐๐ก๐-๐ง๐๐ฃ๐๐ฌ, ๐๐ค๐ฃ๐ฉ๐ง๐๐๐ช๐ฉ๐๐ฃ๐ ๐ฉ๐ค ๐ก๐ฎ๐ข๐ฅ๐๐ค๐ฅ๐๐ฃ๐๐ ๐๐ฃ๐ ๐๐ข๐ข๐ช๐ฃ๐ ๐๐ฎ๐จ๐๐ช๐ฃ๐๐ฉ๐๐ค๐ฃ nature.com/articles/s4200โฆ 2) This study investigates the mechanisms underlying T-cell lymphopenia (low T-cell counts) in severe COVID-19 patients. This is important to understand as lymphopenia correlates with worse disease outcomes.
๐๐ฃ ๐จ๐๐๐ง๐๐ ๐ค๐ ๐ฉ๐๐ ๐๐ฝ2 ๐๐๐ฃ๐ ...
(๐ง๐ฐ๐ณ ๐ญ๐ข๐บ๐ฎ๐ฆ๐ฏ ๐ฐ๐ณ ๐ฌ๐ช๐ฅ๐ด) 2) H5N1 is a highly pathogenic avian influenza virus, commonly known as bird flu. It primarily infects birds, especially poultry, but can also infect humans.
thecattlesite.com/news/how-humanโฆ 2) Scientists are monitoring the bird flu virus for changes that could indicate its ability to spread among humans. A cow-to-human transmission case raised concerns. The virus is typically transmitted through contact with wild birds or infected poultry.
๐๐ฉ๐ข๐ฏ๐ฌ๐ด ๐ต๐ฐ @Crof ๐ข๐ฏ๐ฅ @siamosolocani
๐ต๐ฉ๐ข๐ต ๐ ๐ฉ๐ช๐จ๐ฉ๐ญ๐บ ๐ณ๐ฆ๐ค๐ฐ๐ฎ๐ฎ๐ฆ๐ฏ๐ฅ ๐ต๐ฐ ๐ง๐ฐ๐ญ๐ญ๐ฐ๐ธ๐ค microbiologyresearch.org/content/journaโฆ 2) Samples of HPAIV collected in Iceland between 2022-2023 were analyzed. Three different genotypes of H5N1 clade 2.3.4.4b were found circulating in wild birds in 2022. A novel H5N5 genotype was also identified in 2023.