A recent paper in @AmerAcadPeds provided initial analysis of COVID-19 cases in China, but lacked details that clinicians need to consider as treatment policies develop, says Dr. Kathy Edwards, the Sarah H. Sell and Cornelius Vanderbilt Chair of Pediatrics at @VUmedicine 1/
Edwards says: "Only 1/3 of the cases had confirmed COVID 19 infection and 2/3 were suspected and not confirmed. Most children had few symptoms and recovered quickly. A very small number required more intensive care, but no fatalities were reported. ... 2/
"This paper has several major problems. First only 1/3 of the children had confirmed COVID 19, the majority did not. Second, we are not given any information about whether the children had underlying comorbidities (prematurity, cardiac disease, neurologic disease, cancer)... 3/
"...so the paper does not provide any guidance on those at the greatest risk for severe disease. Finally, the most distressing of of all is that there are no data about the impact of the children on transmission to other people. ..." in 4/
"... These data are sorely needed for us to understand the role of children in transmission to adults." #pedstwitter
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