Need another reason to wear a mask, socially distance, and stay safe?
SARS-CoV-2 gets into cells mostly via the ACE2 receptor. Know what tissue has a lot of ACE2 receptor (besides lungs, gut, heart, etc)?
TESTICLES.
Especially a worry for those young people who "aren't affected as badly" by COVID-19, because you might not be breathing hard, but your dangly bits might be getting permanently toasted.
Don't want your spermatogenesis and steroidogenesis screwed with? Stay home and mask up.
"The main host receptor of the SARS-CoV-2 is angiotensin converting enzyme 2 (ACE2), a major component of the renin-angiotensin-aldosterone system (RAAS). The ACE2 is also involved in testicular male regulation of steroidogenesis and spermatogenesis." ncbi.nlm.nih.gov/pmc/articles/P…
"High level of expression in testis, cardiovascular and gastrointestinal system indicated that SARS-CoV-2 might not only attack the lungs... may severely damage male sexual development for younger males and lead to infertility in an adult male..." ncbi.nlm.nih.gov/pmc/articles/P…
"Testes from COVID-19 patients exhibited significant seminiferous tubular injury, reduced Leydig cells, and mild lymphocytic inflammation." ncbi.nlm.nih.gov/pmc/articles/P…
"... This might indicate that young male patients are at higher risk of testicular damage by COVID-19 than older patients." ncbi.nlm.nih.gov/pmc/articles/P…
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