Tushar Garg, MD Profile picture
Surgery Intern @MGHSurgery | Vascular and Interventional Radiology Resident @MGHImaging @MGHIR1 via @JohnsHopkinsIR and @KEMHospital

Jul 30, 2020, 8 tweets

#FEMMEtrial @NEJM @SIRspecialists: Myomectomy resulted in a significantly better quality of life and lower symptom severity than uterine-artery embolization, although both procedures resulted in substantial improvement as compared with baseline. (1/n)

The mean scores on the health-related quality-of-life domain of the UFS-QOL questionnaire at 2 years were substantially higher than the baseline scores in both groups, but the magnitude of improvement was greater in the myomectomy group than in the UFE group (2/n)

The median length of hospital stay was 2 days (interquartile range, 2 to 3) for the uterine-artery embolization group and 4 days (interquartile range, 3 to 5) for the myomectomy group. (3/n)

The total number of complications in myomectomy group were 50 vs 29 in UFE group (4/n)

9 women (8%) in the uterine-artery embolization group and 5 women (4%) in the myomectomy group reported a pregnancy within 2 years after randomization; there were 6 live births in the uterine-artery embolization group and 4 live births in the myomectomy group. (5/n)

At 2 years, 93% women indicated that they would recommend myomectomy to a friend was 93% and 84% in indicated to recommend UFE, whereas the percentages of women who indicated that they would be willing to undergo the procedure again were 78% and 74%, respectively. (6/n)

Additional fibroid-related procedures were performed in 18 women (16%) in UFE group vs 8 women (7%) in myomectomy group (7/7)

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