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Infectious Diseases and their global story

Apr 5, 2021, 8 tweets

This is COVID in Chile. It's current COVID peak is the higher than it has ever been.

Chile is in the top 5 worldwide in terms of vaccination. Almost 30% are fully vaccinated.

Few countries have been so quick to vaccinate bmj.com/content/372/bm…

Meanwhile, Chile has locked down and closed its borders. The risk on the continent from the expanding epidemic in Brazil is clear.

Q: So what's the problem?
A: P.1 washingtonpost.com/world/2021/04/…

But it's a little more complicated than just the variant itself, which has been a huge problem all on its own. There's also the issue of a) vaccination, though fast, is nowhere near herd immunity and more importantly b) Chile has bet largely on the CoronaVac (Sinovac)

The CoronaVac, also used in Brazil, may not be as effective against P.1
It is a whole killed virus. It does not include the Proline-Proline mutations which prior work on MERS vaccines and Pfizer,Moderna, J&J,Novavax have relied on

nytimes.com/interactive/20… scmp.com/news/china/dip…

**higher than it has ever been

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