#COVID19 - repeated findings in medical reports:
-🦠💥Endothelial Injury
-⬆️ Vitamin D deficiency
-🥴 Immune response
-⬆️Neutrophil Extracellular Traps 🕸 (#NETs)
-⬆️ Autoantibodies, including Antiphospholipid Antibodies
-Immunothrombosis - arterial and venous⬆️blood clots🩸
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-Protect endothelium
-Target vitamin D deficiency 🌞
-Target decreasing excess neutrophil extracellar traps (NETs)🕸
-Decrease likelihood of persistent autoantibodies / autoantibody titers
-Prevent blood clots 🩸
🧐”Neutrophil Extracellular Traps, Antiphospholipid Antibodies and Treatment”mdpi.com/2073-4468/6/1/…
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🧐”Endothelial cell-activating antibodies in COVID-19 “medrxiv.org/content/10.110…
🧐”Conclusions: These data are the first to reveal that patient antibodies are a driver of endothelial cell activation in COVID-19 and add important context regarding thrombo-inflammatory effects of autoantibodies in severe COVID-19.”
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⭐️Pathophysiology: Viral associated vasculitis driven by spike protein, autoantibodies and increased neutrophil extracellular traps, particularly in individuals with genetic or acquired increased vascular risk factors, leading to subsequent increased risk of microthrombosis/microvasular disease, stroke, MI, DVT,PE,etc and autoimmune diseases.
⭐️ #autoantibodies #Covid19
⭐️ #ANA #Covid19 #autoantibodies
⭐️ #VitaminD #ACE2 #Covid19
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