My first PhD article is published!! 🥳
🏭PCBs are persistent organic pollutants and PCBs are “probably in the body of every human” (IARC, 2013)
▪️ Exposure to PCBs in general population is associated with an increased risk of cardiovascular mortality
sciencedirect.com/science/articl…
▪️ Evidence of the impact of background exposure to polychlorinated biphenyls (PCBs) on all-cause mortality is limited
PCB compounds have a strong affinity for fats (lipophilia) and gradually bioaccumulate in adipose tissue over time
Consequently, their main exposure route in the general population is through high-fat food of animal origin
We did not find a relationship between exposure to PCBs and all-cause mortality. However heterogeneity was high
Studies assessing PCB exposure in the general population are lacking
Exposure to PCBs in general population (Controls) is really lower than for an accidental exposure (in Yusho incident for example)
Low-dose effect are still under investigation
It was a collaborative work with @mancini_fr @MKvaskoff @MS_Yahya_ @FrenoyPauline
A nice picture to illustrate biomagnification of PCBs (Polychlorobiphenyls)
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