Thread by @ISNeducation

𝟏/ 𝟏𝟖📊 𝐖𝐡𝐢𝐜𝐡 𝐨𝐟 𝐭𝐡𝐞 𝐟𝐨𝐥𝐥𝐨𝐰𝐢𝐧𝐠 𝐢𝐬 𝐭𝐡𝐞 𝐥𝐞𝐚𝐝𝐢𝐧𝐠 𝐜𝐚𝐮𝐬𝐞 𝐨𝐟 𝐝𝐞𝐚𝐭𝐡 𝐢𝐧 𝐂𝐊𝐃 𝐩𝐚𝐭𝐢𝐞𝐧𝐭𝐬?
@AbduGaip @ISNeducation @Gawad_Nephro @sibgokcay @gag_aggarwal
#ISNTweetorial #tweetorial #Meded #Nephtwitter

@AbduGaip @Gawad_Nephro @sibgokcay @gag_aggarwal 𝟐/𝟏𝟖 𝐂𝐕𝐃 𝐫𝐢𝐬𝐤 𝐢𝐧 𝐂𝐊𝐃:
📌Pts with stages G3-G4 CKD have 2-3X⬆️mortality compared w/ pts w/out CKD, 👉🏽 sciencedirect.com/science/articl…

📌CKD pts exhibit⬆️risk for CV events: 50% of pts with CKD stage 4 to 5 have CVD 👉🏽 kidney-international.org/action/showPdf…
#ISNTweetorial #Nephtwitter

𝟑/𝟏𝟖 📊 𝐖𝐡𝐢𝐜𝐡 𝐨𝐟 𝐭𝐡𝐞 𝐟𝐨𝐥𝐥𝐨𝐰𝐢𝐧𝐠 𝐢𝐬 𝐜𝐨𝐧𝐬𝐢𝐝𝐞𝐫𝐞𝐝 𝐚𝐬 𝐫𝐢𝐬𝐤 𝐟𝐚𝐜𝐭𝐨𝐫 𝐟𝐨𝐫 𝐂𝐕𝐃 𝐢𝐧 𝐂𝐊𝐃 𝐩𝐚𝐭𝐢𝐞𝐧𝐭𝐬?
#ISNTweetorial #tweetorial #Meded #Nephtwitter

𝟒/𝟏𝟖 𝐂𝐕𝐃 𝐢𝐧 𝐂𝐊𝐃 𝐢𝐬 𝐝𝐫𝐢𝐯𝐞𝐧 𝐛𝐲 𝐝𝐢𝐟𝐟𝐞𝐫𝐞𝐧𝐭 𝐫𝐢𝐬𝐤 𝐟𝐚𝐜𝐭𝐨𝐫𝐬:
📌Traditional risks (HTN, DM, smoking, dyslipidemia)
📌Nontraditional risks (vascular calcifications, inflammation...etc)
👉🏽ahajournals.org/doi/10.1161/CI…
#ISNTweetorial #Meded #Nephtwitter

𝟓/𝟏𝟖 📊𝐖𝐡𝐚𝐭 𝐢𝐬 '𝐦𝐨𝐬𝐭 𝐜𝐡𝐚𝐫𝐚𝐜𝐭𝐞𝐫𝐢𝐬𝐭𝐢𝐜 𝐜𝐥𝐢𝐧𝐢𝐜𝐚𝐥 𝐩𝐫𝐞𝐬𝐞𝐧𝐭𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐚𝐜𝐮𝐭𝐞 𝐌𝐈 𝐢𝐧 𝐂𝐊𝐃?
@Gawad_Nephro @elliotktannor @sibgokcay @ISNkidneycare @gag_aggarwal @NamrataYParikh
#ISNTweetorial #Meded #Nephtwitter

@Gawad_Nephro @elliotktannor @sibgokcay @ISNkidneycare @gag_aggarwal @NamrataYParikh 𝟔/𝟏𝟖 𝐓𝐡𝐞 𝐜𝐥𝐢𝐧𝐢𝐜𝐚𝐥 𝐩𝐫𝐞𝐬𝐞𝐧𝐭𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐌𝐈 𝐢𝐧 𝐂𝐊𝐃 𝐩𝐨𝐩𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐢𝐬 𝐨𝐟𝐭𝐞𝐧 𝐚𝐭𝐲𝐩𝐢𝐜𝐚𝐥.
Only 40% of patients with stages G3 to G5 with MI have typical symptoms 👉🏽 ajkd.org/article/S0272-…
#ISNTweetorial #Meded #Nephtwitter

𝟕/𝟏𝟖📊𝐓𝐫𝐮𝐞 𝐨𝐫 𝐟𝐚𝐥𝐬𝐞: 𝐅𝐫𝐚𝐦𝐢𝐧𝐠𝐡𝐚𝐦 𝐞𝐪𝐮𝐚𝐭𝐢𝐨𝐧 𝐡𝐚𝐯𝐞 𝐠𝐨𝐨𝐝 𝐝𝐢𝐬𝐜𝐫𝐢𝐦𝐢𝐧𝐚𝐭𝐢𝐨𝐧 𝐢𝐧 𝐂𝐊𝐃 𝐢𝐧 𝐜𝐨𝐦𝐩𝐚𝐫𝐢𝐬𝐨𝐧 𝐭𝐨 𝐠𝐞𝐧𝐞𝐫𝐚𝐥 𝐩𝐨𝐩𝐮𝐥𝐚𝐭𝐢𝐨𝐧.
@Gawad_Nephro @sibgokcay @aiakl2001
#ISNTweetorial #Meded #Nephtwitter

𝟖/𝟏𝟖 𝐂𝐕𝐃 𝐫𝐢𝐬𝐤 𝐢𝐧 𝐂𝐊𝐃:
📌Framingham equation prediction systematically fall below 'actual risk
👉🏽sciencedirect.com/science/articl…
📌Biomarkers may improve performance of risk prediction models in early CKD
👉🏽linkinghub.elsevier.com/retrieve/pii/S…
#ISNTweetorial #Meded #Nephtwitter

𝟗/𝟏𝟖 📊𝐓𝐫𝐮𝐞 𝐨𝐫 𝐟𝐚𝐥𝐬𝐞: 𝐑𝐞𝐠𝐮𝐥𝐚𝐫 𝐬𝐜𝐫𝐞𝐞𝐧𝐢𝐧𝐠 𝐟𝐨𝐫 𝐜𝐨𝐫𝐨𝐧𝐚𝐫𝐲 𝐚𝐫𝐭𝐞𝐫𝐲 𝐝𝐢𝐬𝐞𝐚𝐬𝐞 𝐢𝐧 𝐚𝐬𝐲𝐦𝐩𝐭𝐨𝐦𝐚𝐭𝐢𝐜 𝐩𝐚𝐭𝐢𝐞𝐧𝐭𝐬 𝐰𝐢𝐭𝐡 𝐂𝐊𝐃 𝐢𝐬 𝐫𝐞𝐜𝐨𝐦𝐦𝐞𝐧𝐝𝐞𝐝
#ISNTweetorial #Meded #Nephtwitter
@Gawad_Nephro @BasuNephro

𝟏𝟎/𝟏𝟖 𝐒𝐜𝐫𝐞𝐞𝐧𝐢𝐧𝐠 𝐟𝐨𝐫 𝐜𝐨𝐫𝐨𝐧𝐚𝐫𝐲 𝐚𝐫𝐭𝐞𝐫𝐲 𝐝𝐢𝐬𝐞𝐚𝐬𝐞 𝐢𝐧 𝐂𝐊𝐃
📌CAD screening in asymptomatic CKD is not recommended. No evidence supporting efficacy of coronary revascularizatn in⬇️death or MI in these pts 👉🏽 jamanetwork.com/journals/jama/…
#ISNTweetorial

𝟏𝟏/𝟏𝟖 𝐒𝐜𝐫𝐞𝐞𝐧𝐢𝐧𝐠 𝐟𝐨𝐫 𝐂𝐀𝐃 𝐢𝐧 𝐂𝐊𝐃 (𝐜𝐨𝐧𝐭.)
📌Exercise test is limited by⬇️functional capacity👉🏽pubmed.ncbi.nlm.nih.gov/18510627/
📌Coronary art. Ca score or CTA has advantage over functional imaging👉🏽sciencedirect.com/science/articl…
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𝟏𝟐/𝟏𝟖 𝐒𝐜𝐫𝐞𝐞𝐧𝐢𝐧𝐠 𝐟𝐨𝐫 𝐜𝐨𝐫𝐨𝐧𝐚𝐫𝐲 𝐚𝐫𝐭𝐞𝐫𝐲 𝐝𝐢𝐬𝐞𝐚𝐬𝐞 𝐢𝐧 𝐂𝐊𝐃 (𝐜𝐨𝐧𝐭.)
Dialysis pts have⬆️ risk for coronary artery stenosis w/⬆️CAC scores, but 'risk is ⬇️than in pts without CKD with similar CAC scores.👉🏽 ncbi.nlm.nih.gov/pmc/articles/P…
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𝟏𝟑/𝟏𝟖📊𝐓𝐫𝐮𝐞 𝐨𝐫 𝐟𝐚𝐥𝐬𝐞: 𝐂𝐚𝐫𝐝𝐢𝐚𝐜 𝐭𝐫𝐨𝐩𝐨𝐧𝐢𝐧𝐬 𝐚𝐫𝐞 𝐟𝐫𝐞𝐪𝐮𝐞𝐧𝐭𝐥𝐲 𝐧𝐨𝐫𝐦𝐚𝐥 𝐢𝐧 𝐚𝐝𝐯𝐚𝐧𝐜𝐞𝐝 𝐂𝐊𝐃
#ISNTweetorial #tweetorial #Meded #Nephtwitter

𝟏4/𝟏𝟖 𝐌𝐚𝐫𝐤𝐞𝐫𝐬 𝐨𝐟 𝐌𝐲𝐨𝐜𝐚𝐫𝐝𝐢𝐚𝐥 𝐈𝐧𝐣𝐮𝐫𝐲 𝐢𝐧 𝐂𝐊𝐃
📌Dynamic changes in troponin⬆️specificity for Dx MI in ESKD👉🏽 sciencedirect.com/science/articl…
📌Troponins are frequently ⬆️ in advanced CKD 👉🏽 academic.oup.com/clinchem/artic…
#ISNTweetorial #tweetorial #Nephtwitter

𝟏𝟓/𝟏𝟖 𝐌𝐚𝐫𝐤𝐞𝐫𝐬 𝐨𝐟 𝐦𝐲𝐨𝐜𝐚𝐫𝐢𝐝𝐚𝐥 𝐢𝐧𝐣𝐮𝐫𝐲 𝐢𝐧 𝐂𝐊𝐃 (𝐜𝐨𝐧𝐭.) Although sensitivity of high-sensitivity troponin I in Dx of MI is not modified by kidney function, its specificity⬇️with GFR decline 👉🏽 jasn.asnjournals.org/content/29/2/6…
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𝟏𝟔/𝟏𝟖📊𝐓𝐨𝐫𝐅: 𝐀𝐝𝐯𝐚𝐧𝐜𝐞𝐝 𝐂𝐊𝐃 𝐰/ 𝐬𝐭𝐚𝐛𝐥𝐞 𝐜𝐨𝐫𝐨𝐧𝐚𝐫𝐲 𝐝𝐢𝐬𝐞𝐚𝐬𝐞 & 𝐦𝐨𝐝𝐞𝐫𝐚𝐭𝐞/𝐬𝐞𝐯𝐞𝐫𝐞 𝐢𝐬𝐜𝐡𝐞𝐦𝐢𝐚, 𝐢𝐧𝐢𝐭𝐢𝐚𝐥 𝐢𝐧𝐯𝐚𝐬𝐢𝐯𝐞 𝐬𝐭𝐫𝐚𝐭𝐞𝐠𝐲 𝐢𝐬 𝐞𝐟𝐟𝐢𝐜𝐢𝐞𝐧𝐭 𝐭𝐡𝐚𝐧 𝐜𝐨𝐧𝐬𝐞𝐫𝐯𝐚𝐭𝐢𝐯𝐞 𝐨𝐧𝐞
#ISNTweetorial

𝟏𝟕/𝟏𝟖 𝐌𝐚𝐧𝐚𝐠𝐞𝐦𝐞𝐧𝐭 𝐨𝐟 𝐂𝐀𝐃 𝐢𝐧 𝐂𝐊𝐃
Among advanced CKD pts w/ stable coronary disease, and moderate/severe ischemia, initial invasive strategy, as compared w/ conservative strategy, didn't ⬇️'risk of death or nonfatal MI👉🏽
nejm.org/doi/full/10.10…
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𝟏8/𝟏8 CKD pts are not enrolled sufficiently in CVD trials. More recruitment is needed for strong evidence.
𝐉𝐨𝐢𝐧 𝐧𝐞𝐱𝐭 𝐍𝐮𝐚𝐧𝐜𝐞𝐬 𝐢𝐧 𝐍𝐞𝐩𝐡 𝐰𝐞𝐛𝐢𝐧𝐚𝐫 "Coronary Artery Revascularization Strategy in 'Advanced Stage of CKD"

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