1/ Study of ~9M people in NYS
medrxiv.org/content/10.110…
May: NYS adopted CDC guidance for fully-vaxxed
June: end of NYS’ state of emergency (⬇️mask-wearing, distancing etc)
July: CDC recommended mask usage for fully-vaxxed based on transmission levels
July: Delta became dominant
2/ COVID vaccine effectiveness vs HOSPITALIZATION:
Among 18-49 year-olds:
Pfizer/Moderna: >90%
* except June with 87% for Moderna
J&J: >90%
* except June with 54%
* related to behavior? (see #1)
3/ COVID vaccine effectiveness vs HOSPITALIZATION:
Among 50-64 year-olds:
Pfizer/Moderna: >90%
J&J: 87-93%
STABLE OVER TIME.
4/ COVID vaccine effectiveness vs HOSPITALIZATION:
Among ≥65 year-olds:
Pfizer: 93-95% (May)➡️86-90% (August)
Moderna: 96-97% (May)➡️93-94% (August)
J&J: 80-90%
5/ COVID vaccine effectiveness vs lab-confirmed CASES:
Among 18-49 year-olds:
Pfizer: 94%➡️66%➡️69% (May-July)
Moderna: 97%➡️77%➡️78% (May-July)
J&J: 89%➡️52%➡️70% (May-July)
6/ COVID vaccine effectiveness vs lab-confirmed CASES:
Among 50-64 year-olds:
Pfizer: 95%➡️72%➡️76% (May-July)
Moderna: 97%➡️86%➡️83% (May-July)
J&J: 87%➡️73%➡️76% (May-July)
7/ COVID vaccine effectiveness vs lab-confirmed CASES:
Among ≥65 years-olds:
Pfizer: 92%➡️79%➡️78% (May-July)
Moderna: 96%➡️87%➡️84% (May-July)
J&J: 82%➡️79%➡️71% (May-July)
8/ These data support giving additional doses of vaccine to persons 65+ to reduce risk of disease and hospitalization.
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