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Official Twitter account for the International Vasculitis and ANCA Workshop 2022. 3rd - 6th April 2022.

Apr 5, 2022, 8 tweets

Parallel Session I: Epidemiology

Negative Versus Positive Antineutrophil Cytoplasmic Antibody Granulomatosis with Polyangiitis: A Case-Control Study

Ms Marta Casal Moura

@martacasalmoura

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AAV represents a disease spectrum.

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How do ANCA negative and positive GPA patients differ?

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How was ANCA-negative GPA defined?

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Conducted a case control study.

1058 patients identified overall, 110 ANCA negative GPA.

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Results

There were important differences in characteristics - BVAS scores, alveolar haemorrhage.

Also pathological differences.

Differences in how they were treated and their subsequent clinical course.

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Small numbers of seroconverters.

Increased numbers of relapses.

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Conclusions

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