Thread by @kidney_boy

Next up fellow Channeler, @AnnaGaddy to talk about urine Chemistries to Predict and Monitor Response to Diuretics. She’s an Assistant Professor of Medicine. #NKFClinicals

Interesting topics #NKFClinicals

Heart failure is a disease of inadequate sodium homeostasis. #NKFClinicals

Diuretics try to bring down ECF while in the long term patient returns to Na in = Na out (sodium intake is the dotted line)

First tweet I have seen on a slide at #NKFClinicals

I’s, O’s and daily weights are lying to you. #NKFClinicals

What is important is negative sodium balance not negative fluid balance. #NKFClinicals

spot urine Na 1-2 hours after loop diuretic predicts diuretic responsiveness. Note that you have remove the GFR correction for BSA. #NKFClinicals

48 hour urine sodium predicted mortality and NGAL, guessing you are more concerned about the former. #NKFClinicals

She emphasizes that measurement of diuretic responsiveness should focus on urinary sodium not urine volume #NKFClinicals

Brilliant talk. I was very skeptical when I read the title that there would be enough and quality data. Crushed it.