#EULAR2022
How to treat (HOT)
Difficult to treat RA
Definition:
#EULAR2022
How to treat (HOT)
Difficult to treat RA
🟣 FMS is asso with more severe RA
🟣 Pts with D2T RA have higher comorbidity burden
🟣 Obesity is also a mediator of non Response
#EULAR2022
How to treat (HOT)
Difficult to treat RA
This was interesting
🟢 Pts with D2T RA may have a pausi immune phenotype
🟢 This might explain poor response to Rx
#EULAR2022
Pts with D2T RA have
🟣 ⬆️Comorbidities, DMRD ADRs, FMS, Depression, Anxiety
🟣⬇️ QOL
🟣 3 phenotypes have been found
🟪 Rx Non-Adherent
🟪 Obese with Pain syndrome
🟪 True Refractory
#EULAR2022
How to treat (HOT)
Difficult to treat RA
🟣 Adverse events contribute max to treatment non-adherence
🟣Relation with HC provider the most Imp facilitator
🟣D2T RA has higher economic burden then nonD2T RA
#EULAR2022
How to treat (HOT)
Difficult to treat RA
Points to consider for Managing D2T RA
#EULAR2022
How to treat (HOT)
Difficult to treat RA
Overarching principles and Research agenda
#EULAR2022
How to treat (HOT)
Difficult to treat RA
Summary slides
Awesome talk 👌🏻🤩
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