#EULAR2022
What is New (WIN)
Osteoarthritis – evolving treatments
This talk is a must-watch on-demand - highly recommended
🗝Proposed NICE-UK guidelines for
#EULAR2022
🗝Most trials have tried correcting catabolic pathway
🗝 Most trials in OA have failed
🗝Cartilage though sparsely cellular/vascular exquisitely sensitive to injury
🗝 Max polymorphism in OA is found in the Anabolic pathway
#EULAR2022
What is New (WIN)
Osteoarthritis – evolving treatments
🗝Shear stress leads to damage while compression leads to regeneration
🗝Has been utilized in Joint distraction showing good results
#EULAR2022
What is New (WIN)
Osteoarthritis – evolving treatments
🗝Pain might not be the perfect outcome in OA trials
🗝Sprifermin looks promising 👉🏻 effect was more pronounced in patients with progressive disease
🗝 newer drugs on Horizon
#EULAR2022
What is New (WIN)
Osteoarthritis – evolving treatments
🗝 The right subgroup shows the right results
🗝 CANTOS showed patients on IL1i required lesser joint replacement
#EULAR2022
What is New (WIN)
Osteoarthritis – evolving treatments
the future looks brighter than bleeker for OA patients
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