Karen Magraith Profile picture
GP. Past president, Australasian Menopause Society. HCW wellbeing. Bushwalker. Views my own. lutruwita/Tasmania #Menopause

Oct 27, 2022, 9 tweets

Next session. Hormones.
First speaker Prof Alfred Mueck.
Principles to select estrogens.
Conjugated equine estrogens - contain a lot of substances, in variable amounts.
Suggests we move away from its use. #IMS2022

Estradiol containing COCPs. Took a while to develop because of bleeding issues.
Now we have pills with good cycle control, because of the progestogen. Dienogest or nomegestrol. #IMS2022

Next speaker Prof Nick Panay. (UK)
Optimizing hormone therapy through choice of progestogen/progesterone.
#IMS2022

Observational data suggest that type of progestogen has an impact on risk of breast cancer. Micronised progesterone not associate with inc risk up to 5 yrs of use. #IMS2022

Micronised progesterone may have neutral effect on CV system but more information needed. #IMS2022

What are the options for women with progestogen/progesterone intolerance?
Some research going on with (off label) use of low dose LNG IUS with regular endometrial surveillance. #IMS2022

Conclusion. Not all progestogens are the same. #IMS2022

Final speaker. Prof Andrea Genazzani (Italy).
Behind estrogens and progesterone: Menopause and neurosteroids. #IMS2022

It’s complicated! #IMS2022

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