Mackenzie Mathis, PhD Profile picture
Scientist merging adaptive motor control & machine learning | 🐭@deeplabcut πŸ¦“@cebraAI | @ELLISforEurope Scholar | (same @ on bluesky)

May 3, 2023, 7 tweets

πŸ¦“ Self-supervised multimodal ML is promising the next AI breakthrough - in our new work published in @Nature, we debut @cebraAI: for self-supervised hypothesis- and discovery-driven science.

πŸ“ doi.org/10.1038/s41586…
πŸ’»github.com/AdaptiveMotorC…
πŸ¦“ cebra.ai
πŸ§΅β¬‡οΈ

First, this is a story about people πŸ₯³ @stes_io & @jinnnnnleeΒ  are co-first authors and it was absolute pleasure to work with them & see the πŸ¦“ CEBRA magic come to life. A few happy/fun bits in the @Nature research briefing!

πŸ”—nature.com/articles/d4158…

The work: we focused in on 4 open-access datasets: synthetic, hippocampus, sensorimotor, and vision across species & recording methods to show the general performance and many features of #CEBRA

cc @AllenInstitute @sejdevries @PresNCM & more (πŸ™)

The strength of CEBRA is the flexibility & performance: no generative model = no restrictions on data, & it can be used unsupervised (Time) or w/labels (Behavior).

Here, we demo on hippocampus with CEBRA-Time and then do hypo. testing for a quantitative readout of model fit!

One big #CEBRA moment for us was seeing the impressive video decoding results:

🐭🧠+πŸŽ₯->πŸ¦“=

- high perf. >95% accuracy at frame prediction πŸ”₯
- highly similar latents across Neuropixels & 2-photon data βœ…
- differences in performance across the visual system of 🐭

To be continued...
we won't tweet all the science today,
so stay tuned for more highlights later πŸ–€πŸ¦“πŸΎ

βœ¨πŸ¦“πŸ–€ Our Research Briefing can now be found at rdcu.be/dbhwe

- the problem, our solution, and future directions … 🚨including how CEBRA is not limited to neural dataπŸš¨β€” if you use t-SNE or UMAP, consider using CEBRA for more consistent and higher accuracy results

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