Julia Seller Profile picture
Cardiologist in Marina Salud Hospital (Dénia) Heart failure unit. Every month 🗓 Top3 #HF trials

May 23, 2023, 11 tweets

🧵 What not to miss at the congress
#HeartFailure2023 @escardio

🏆 HERMES

📲 Implementing non-invasive telemedicine services based on mHealth combining teleintervention ➕ telemonitoring in HF-patients with a recent 🏥 admission due to HF decompensation

🎯 is effective in preventing fatal and non-fatal CV events.

🔷 PARAGLIDE ➕PARAGON

Sacubitril/valsartan ⬇️ CV and renal events in HFmrEF and HFpEF.

📁 academic.oup.com/eurheartj/adva…

🔷 Phase 1 trial➡️NI006 had a favorable safety profile in patients with ATTR cardiomyopathy

💊 At doses of at least 10 mg per kg, amyloid-load surrogates appeared to be ⬇️

📁 nej.md/42FG6P6

🔷 ENACT- HF

UNa-guided vs SOC:

⬆️ Natriuresis 🧂
⬆️ Natriuresis 🧂 ➕diuresis 💦
⬇️ length of stay 🏥

🔷 MODA 🇪🇸

Dapagliflozin in chronic HF and optimized therapy results:

🎯 global reverse remodeling of🫀 structure, including LA volumes and improvement in LV geometry

⬇️ NT-proBNP

📁 onlinelibrary.wiley.com/doi/abs/10.100…

🔷 CLOROTIC 🇪🇸

adding oral HCTZ (doses adjusted to eGFR) to IV furosemide:

⬆️ Diuretic response in AHF 💦

🧩 Independent of initial eGFR

⬆️ Response in patients with better baseline renal function💦

🔷 Effect of iv iron replacement
on recurrent HF🏥 and CV ☠️ in HF and iron deficiency 🔩

FAIR-HF➕CONFIRM-HF➕
AFFIRM-AHF

⬇️in recurrent HF 🏥 and CV mortality.

🧩Results were nominally consistent across the subgroups studied

📁 onlinelibrary.wiley.com/doi/10.1002/ej…

🔷 STEP-HFpEF programm

➡️ is testing semaglutide effects on symptoms, physical limitations & exercise function in obesity HFpEF phenotype.

📁 jacc.org/doi/10.1016/j.…

🔷 Slides 🔝

In- 🏥 Initiation of HF therapies @ShelleyZieroth

🔔 HF Guidelines: new evidence in 2023 (not available in 2021) by Piotr Ponikowski

❤️ And of course, the reunion with great friends‼️

See you in Lisbon 🇵🇹

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