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Inescapable Immune Escape Pandemic
@GVDBossche
Dr. Geert Vanden Bossche
1. How mRNA Vaccines and Vaccine Breakthrough Infections Drive Viral Immune Escape Dynamics
🔹 The development of herd immunity to COVID-19 has been hindered by mRNA vaccines and vaccine… twitter.com/i/web/status/1…
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2. Only Trained Cellular Innate Immunity Yields Durable Protection During An Immune Escape Pandemic
🔷 During a pandemic of an acute self-limiting viral infection, the best way to protect ourselves is not through vaccination but through training of our innate immune… twitter.com/i/web/status/1…
@GVDBossche 🧵
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3. Is Covid Vaccine Protection Durable?
🔷 People who have been vaccinated against COVID-19 are still benefiting from protection against severe illness, but relying solely on weak and short-lived antibodies means that protection is suboptimal and only temporary.… twitter.com/i/web/status/1…
@GVDBossche 🧵
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4. Is the Covid-19 Pandemic Calming Down?
🔷 Currently, the absence of high hospitalization and mortality rates due to COVID-19 might create a false sense of security. However, ongoing evolutionary dynamics of the virus pose an imminent threat to vaccinated… twitter.com/i/web/status/1…
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The Insidiousness of Reduced Pathogenicity in Covid-19
🔷 Don't be fooled into thinking that a decrease in the pathogenicity of the virus means we have achieved herd immunity and only need to bother about an annual update, as in the case of seasonal flu vaccines.… twitter.com/i/web/status/1…
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Omicron Causes Enhanced Large-Scale Immune Escape Dynamics
🔷The advent of Omicron caused viral immune escape dynamics to reach a point of no return, transforming the immune escape pandemic into an 'inescapable' self-catalyzing chain of enhanced immune escape,… twitter.com/i/web/status/1…
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Trained-Cell-Based Innate Immunity: How It Protects the Unvaccinated from Covid19 Escape Variants
🔷 Trained-cell-based innate immunity provides strong sterilizing immunity, so unvaccinated people are not to blame for natural immune selection and dominant propagation… twitter.com/i/web/status/1…
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Breakthrough Infections Via Diminished Neutralizing Capacity of Vaccine-Induced Antibodies
🔷 Mass vaccination generated an immune escape landscape where vaccine breakthrough infections enabled Omicron to resist the neutralizing capacity of antibodies, leading to an… twitter.com/i/web/status/1…
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Breaking the Blockade: SARS-CoV-2 Adapting to Vaccine Immunity
🔷 With more people getting vaccinated against COVID-19, it is important to know that the virus more readily adapts, selecting variants capable of breaking through suboptimal vaccine-mediated immune… twitter.com/i/web/status/1…
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Risks of mRNA Covid-19 Vaccines: Impact on Individual and Public Health
🔷 mRNA-based Covid-19 vaccines are considered problematic from both an individual and public health perspective due to their ability to shift the focus of the immune response to poorly… twitter.com/i/web/status/1…
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