Thread by @a_nineties

guess who just got into the EMA clinical data publication system :) you have to go all digital citizen but then you get clinical study reports! hundreds of megabytes of files per entry. https://t.co/nsyRSqMp8mclinicaldata.ema.europa.eu/web/cdp/home

for example: here's the final C4591001 protocol amendment!

nope lol there's another final protocol amendment?

i know im gonna be spending hours making sense of this stuff. the top two entries have 10 and 17 documents respectively? weird as hell

my browser crashed, but there's lots of material on C4591007, the kids study, including the narrative-sensitive file listing serious adverse events. dozzens of seizures and ICU treatment led to postponement of study intervention in a 3yo.

there's also an interim study report, and they were really using one of the OG C4591001 batches 👀

why do 6/17 comirnaty authorizations not have "tozinameran" as active substance, instead "COVID-19 mRNA vaccine (nucleoside-modified)", including the first four and the most recent two?

c4591044 is the hilarious bivalent trial. like 800 participants, the first entire cohort is just left out of the data and there are precisely 7 days post-dose safety data available. ~30% of the 3x jabbed study population had already had covid 😂

👀 ab titres 1 week after dose 2 was higher than 1 month after dose 2, but 1 week after dose 3 was LOWER than 1 month after dose 3. also note this graph is LOG scale. 23 c4591001 patients were boostered. that's the science behind dose 3.

also, how directly to jail will i go if i just upload all the documents to ? they're guaranteed watermarked to my account. maybe i should read the T&C 🤔mega.nz

an average of 2.3 weeks of safety data for C4591007. mRNA for kids was based on two weeks of safety data. jesus christ