Pleased to share exciting results from @dasgobardhan's and my lab, on treating TB using a known Ayurvedic molecule. journal.frontiersin.org/article/10.338…
.@dasgobardhan Sāl, also called 'Tree of Vishnu', produces Bergenin. For the first time, we discover its potent role in treating TB journal.frontiersin.org/article/10.338…
@dasgobardhan A novel route to kill TB. Pleased to share @the_hindu's report on the discovery from @dasgobardhan's and my lab. thehindu.com/sci-tech/scien…
Improving BCG vaccine. Discovery from @dasgobardhan's and my lab in the wake of recent BCG efficacy data from UK. grin.news/meet-the-men-b…
Do watch this wonderful episode of #BharatKiBaat, directed by Pallavi Joshi, on Indian science. It also features the work done on combating Tuberculosis in @dasgobardhan's and my lab, specifically Prof Das' seminal discovery viz Stem Cells and TB. Thanks.
@dasgobardhan Pleased to share exciting results from @shailjasingh75's and my lab, on the discovery of a molecule that inhibits a crucial mechanism employed by the Malaria parasite for propulsion and motility. Report on this Myosin Motor Blocker by @kalyanray30. deccanherald.com/national/jnu-b…
Happy to report in collaboration with Prof @dasgobardhan, that the Ayurvedic herb component Luteolin, a potassium channel inhibitor, significantly enhances anti-tuberculosis BCG vaccine efficacy. We propose adding Luteolin to the BCG vaccination protocol. journals.plos.org/plospathogens/…
Delighted to share results from our four year collaboration with @shailjasingh75, @dasgobardhan and Ram from BHU, on the discovery of drug-like molecules that modulate host NAD metabolism and combat Tuberculosis & Malaria infection. Report by @rohanduaTOI. timesofindia.indiatimes.com/india/jnu-bhu-…
Happy to share exciting results from @dasgobardhan's and my lab, that the Ayurvedic herb component Luteolin when administered along with the anti-TB drug Isoniazid promotes anti-TB immunity, reduces the length of TB treatment, and prevents disease relapse. journals.plos.org/plospathogens/…
Pleased to share important results published yesterday by my colleagues @shailjasingh75, Soumya, Ram, and I, that a novel small molecule Glycoside-2 potently kills multiple Leishmania strains, almost as well as the expensive drug amphotericin B. frontiersin.org/articles/10.33…
Delighted to share results from my lab and that of Dr @shailjasingh75, led by Dr Jhalak Singhal, on the discovery that host SUMOylation negatively regulates protective immune responses & promotes Leishmania survival. Opens a new avenue for drug discovery. indiatoday.in/science/story/…
The malaria parasite glides on the surface of our red blood cell before invading it.
Published today, we show, in collaboration with @shailjasingh75 & Dr Saumya, that blocking glideosome protein phosphorylation and palmitoylation blocks parasite invasion. frontiersin.org/articles/10.33…
Pleased to share an exciting discovery from my lab and that of @shailjasingh75 that opens a new path for malaria treatment. We find an anti-Hepatitis virus drug to be extremely potent against drug-resistant malaria. Link to paper: journals.asm.org/doi/10.1128/aa… timesofindia.indiatimes.com/city/delhi/in-…
On #WorldMalariaDay2023, happy to share findings published today from the labs of @shailjasingh75 and mine among others, that an anti-Cancer drug potently inhibits a vital mitochondrial protein of the Malaria parasite. Exciting road ahead. Link to paper: sciencedirect.com/science/articl…
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