Timing of autoimmune haemolytic anaemia post BMT, from Marina Karakatanza #bbts2017
True AIHA post BMT is donor ab against donor antigen 'donor to donor' #bbts2017
Sorry for blurry pics -blame the NHSBT phone!! #bbts2017
Cold AIHA onset 5-12/12 due to reconstituting B and T cells, Warm 6-12/12 & due to mature B lymphocytes #bbts2017
Risk factors include GvHD, T cell depletion, transplant for non malignant disorder, MUD transplant #bbts2017
Risk factors relate to depth of lymphopenia and immune system activation #bbts2017
REcommended treatments for post BMT AIHA include steroid, IVIg, rituximab #bbts2017
But AIHA post BMT can be very refractory. RR for steroids/IVIg 10%, 46% ritux in adults (83% children) sciencedirect.com/science/articl… #bbts2017
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