We talked about special requirements today as well. Irradiated components required for T cell immunodeficiency or when donor/recip HLA types are similar. Full guideline is here
b-s-h.org.uk/guidelines/gui…
#BSHTIP
Important examples are
Chemotherapy with purine analogues (eg fludarabine) BUT NOT most chemotx
Hodgkin lymphoma
Post allo or auto BMT
HLA selected platelets
Donation from 1st degree relative
but NOT HIV
If in doubt, check before prescribing! #BSHTIP
CMV negative components rarely required. SaBTO guidelines here gov.uk/government/new…
Essentially only for
Elective transfusion in pregnancy
IUT
Neonates
#BSHTIP
Washed components for severe recurrent allergic reactions. Washed plasma is not available!!! #BSHTIP
More info on allergic reactions here onlinelibrary.wiley.com/doi/full/10.11…
HLA selected platelets usually only for those with platelet refractoriness and HLA abs demonstrated. Other causes of refractoriness =
sepsis
splenomegaly
drugs
#BSHTIP
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