Dr Suzy Morton 🅾️➕ Profile picture
Oct 18, 2018 21 tweets 7 min read Read on X
Next up Heidi Doughty talking on transfusion support for mass casualty events and updated guidance. Sadly a very important part of our work #F2FNHSBT
Review article in Vox Sanguinis Ramsey et al. onlinelibrary.wiley.com/doi/abs/10.111…
Although some patients need MHP, recent disasters have shown a couple of units used per patient. But relates to GSWs rather than IUDs... No clear answer #F2FNHSBT
Repeat visits to theatre often required with ongoing transfusion requirements. Important to get it right first time #F2FNHSBT
Not just mass casualty incidents but all emergency preparedness e.g. reduced supply from weather/pandemic flu and so on. Have you read your hospital's plan? Is blood management included? #F2FNHSBT
TPs play a key role in supporting clinical staff #F2FNHSBT
We have run table top and mock exercises locally. Very useful to identify what works and what doesn't #F2FNHSBT
Also need a stand down plan. Normal service can't resume straight away... #F2FNHSBT
Lots of resources from over the pond here asprtracie.hhs.gov/technical-reso… #F2FNHSBT
Issues with patient identification and numbering always topical. Sequential numbering is not safe #F2FNHSBT
NHS England guidelines on track for release over the summer. Clinical Guidelines for Major Incidents and Mass Casualty Events #F2FNHSBT
Triage of patients is important but difficult. P1/2/3 system may be obsolete. P1s to MTCs and P2s to TUs. Most hospitals will get patients, even if not a MTC. Everyone needs a plan! Check your regional MI plan to see what your hospital is assigned #F2FNHSBT
Principles of MHP are maintained but need modifications. Substitutions need to be clear and available. As always communication and portering need to be prioritised #F2FNHSBT
Biggest risk is ABO incompatibility. RhD and kell prioritised for women <50y #F2FNHSBT
Use of red cells in mass cas events is bimodal. Median is 2 units but a few patients will need far more #F2FNHSBT
Danger of overordering is real and will cause harm unless we have clear plans #F2FNHSBT
How to manage additional donors? Peak in new donors at about a week. Supply chain cannot manage huge peaks. Need to encourage donors to donate over a longer time frame #F2FNHSBT
'Surgical tail' with repeated visits to theatre over weeks/months- also requires increased supply. Rescheduling of cancelled surgery also needs more blood. Increased demand is ongoing for a long time #F2FNHSBT
Use of imported plasma for young patients is topical. Balance of risk is important. Substitute to reduce the impact of delay #F2FNHSBT
Octaplas has recently increased shelf life for thawed component to 5 days for use in unanticipated major haemorrhage, in line with UK FPP #F2FNHSBT
medicines.org.uk/emc/product/41…
Ability to return unused units to NHSBT would be important to help demand in subsequent weeks. Currently not possible though #F2FNHSBT

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More from @TransfusionWM

Aug 19, 2022
I had a personal request to do a tweetorial for the #haemSpRs on haemovigilance. Here goes. A #blooducation 🧵
Haemovigilance is a systematic surveillance of adverse reactions and adverse events related to transfusion’ with the aim of improving transfusion safety.
transfusionguidelines.org/transfusion-ha…
We are very lucky in the UK to have @SHOTHV1, one of the first in the world to collate adverse events relating to transfusion - since the 1990s.
Read 25 tweets
Aug 17, 2022
This morning I met with the chair and vice chair of the Midlands Regional Transfusion Committee, the Midlands Patient Blood Management Practitioner and the Customer Services Manager. What are their roles and what does the RTC do?
A #blooducation 🧵
RTCs serve to bring together Hospital Transfusion Committees to discuss best practice, implement new guidance and provide educational resources and events. They are run by clinicians and scientists working in hospitals, supported by @NHSBT.
There are 7 RTCs in England transfusionguidelines.org/uk-transfusion… (NB map hasn’t been updated to reflect recent changes) @london_rtc @NEY_RTC @SW_RTC @SEC_RTC
Read 15 tweets
Aug 5, 2022
Teaching our incoming haematology doctors today about transfusion in haematology patients. So who needs irradiated blood and why? A #blooducation🧵
All blood in the UK is leucocyte reduced (except granulocytes, but that’s another story). Despite this, a unit of red cells or platelets can have around a million residual white cells, mostly lymphocytes.
(for the #haemSpRs, that’s < 5 x 10^6 leucocytes/unit in > 99 % of units and < 1 x 10^6 leucocytes/unit in > 90% of units, both with 95% statistical confidence)
nhsbtdbe.blob.core.windows.net/umbraco-assets…
Read 10 tweets
Aug 4, 2022
Every doctor starting in a new trust does transfusion training as part of their mandatory training. But why?
50ml ABO incompatible blood can kill a patient. ABO antibodies are naturally occurring (“everyone” has them) and they are IgM; they can activate complement and cause *immediate* intravascular haemolysis, causing release of free haem, endothelial activation, renal failure and DIC.
In most hospitals, blood banks require 2 samples (one may be historic) before releasing group specific (non-O) blood for a patient. This is to increase the chances of identifying a *wrong blood in tube* (pt whose blood's in the tube is not the pt whose details are on the outside)
Read 11 tweets
Aug 4, 2022
Transfusion tips for new #haemSpRs, a thread
As a new ST3 I remember being told to book onto the @NHSBT transfusion course learningcentre.nhsbt.nhs.uk/catalog?pagena… and wondering why I needed to learn about transfusion ... 🙈
It can be difficult to know where to start with transfusion – you can’t go on a ward round to find patients. BUT you do start with lab induction and your helpful #BMSes will show you around.
Read 7 tweets
Oct 3, 2020
Excellent session on emergency paediatric transfusion #AABB20. Cyril Jacquot talking on pre hospital transfusion and summarising the literature.
28 day mortality following haemorrhage is higher in children than adults (unpublished data and substudies from PROPPR and PROMMTT)
Observational studies of large numbers of patients but with only very small numbers of paediatric patients suggest that pre hospital blood is not associated with an excess of transfusion reactions and in some studies is thought to have improved survival.
Whole blood, group O, high titre neg, used in paediatrics in Pittsburgh appears to be safe with no haemolysin-mediated haemoylsis in non group O patients (Leeper et al JAMA Pediatrics 2018) ncbi.nlm.nih.gov/pmc/articles/P…
Read 12 tweets

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