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It'sME(Jaime) @exceedhergrasp1
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Given food that had cheese in it on Thurs afternoon. Thought I noted the taste but told myself no, b/c restaurant made it clear no dairy. Late Friday night started having problems breathing. Now (Sat) intermittently gasping like a fish on dry land.
This is a delayed Type IV hypersensitivity reaction, say the interwebs. When you get a reaction about 48 hrs after the 'initial insult'. It's slow b/c it requires replication of T cells that have an antigen to one of that food's proteins on their surface.
This is similar to what happens in #celiac. It's also possible for the response to come from basophils or eosinophils. Sometimes it's IgE-based, sometimes it's not. It appears we know little, or I feel there'd be sub-classifications for the reaction types.
Looking for things that might attenuate the reaction and came across an article suggesting berberine. Too bad I'm all out of goldenseal and oregon graperoot. link.springer.com/article/10.100…
So I'm falling back on the old standbys: charcoal to sop up whatever TF I've ingested that my body feels is an existential threat, hydrochloric acid and digestive enzymes, and then a heaping pile of turmeric and crucifers: hindawi.com/journals/iji/2…
BTW delayed hypersensitivity reactions are more likely if you have #EDS or #hypermobility: sciencedirect.com/science/articl…
Ppl knock IgG testing but it did help me identify all the foods that I react to, including milk products. And speaking of edge-of-modern-sci stuff, in this search I stumbled across a few articles re: hypersensitivity to nickel...
...and, subsequently, dental amalgam. So the idea would be that you're not actually being poisoned with mercury so much as you are having a consistent Type IV hypersensitivity reaction to it. And such reactions are common in #EDS #Sjorgens #lupus, e.g.
This is the first I've heard of this framing, and it's interesting. Articles from 2014 read "metal hypersensitivity: fact or fiction?!", but articles that came out this year seem (at least at a glance) far more scholarly/legit.
Finally, a shout-out to the 2 (two) hospitals where docs swore cortisol hypersensitivity was impossible when I was literally experiencing it in front of them. link.springer.com/article/10.100…
Update: digestive enzymes & HCl, then charcoal about 15-20 min later made me feel a bit better, but it was when I ate the heaping pile of crucifers with a half-ton of turmeric that I finally stopped feeling dizzy and breathless.
Today it's still a little bit harder to find air than it should be, but I'm not gasping. And folks, this is a MILD IgE reaction or an extreme IgG intolerance depending on how you're looking at it. Obviously don't ride out anaphylaxis at home with some brussels sprouts, ok? Ok.
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