, 10 tweets, 6 min read Read on Twitter
There are three parallel sessions to choose from but I will be live tweeting the talk by Nur Hasan, CSO of @CosmosID with "Unlocking the microbiome with bias-free, affordable, metagenomic sequencing and best-in-class cloud bioinformatics"
#MBCongress2019
@CosmosID Nur Hasan: The microbiome is broadly implicated with health and disease. Therefore, it is a target for many diagnostic and therapeutic approaches. Interpretation of cause and effect, and understanding pathways all are still not well established.
#MBCongress2019
@CosmosID Nur Hasan: You need to have high resolution strain-level data for better functional insight. A strain is the clinically informative and actionable unit, not a species.
#MBCongress2019
@CosmosID Nur Hasan: Different Lactobacillus casei strains are used for making Wisconsin cheese, chardonnay wine, or yogurt. Same species, very different strains.
#MBCongress2019
@CosmosID Nur Hasan: We offer end-to-end sequencing and analysis services, as well as bioinformatics analysis and visualization, even for people with little bioinformatics background.
#MBCongress2019
@CosmosID Nur Hasan: There are several different next-generation sequencing methods - which method for which purpose?
Amplicon sequencing has served us well, but has limitations. Shotgun sequencing adds to specificity. Need good reference databases.
#MBCongress2019
@CosmosID Nur Hasan: Within shotgun metagenomics, choice of sequencing depth depends on e.g. % host DNA, diversity in your sample, desired information, and purpose.
#MBCongress2019
@CosmosID Nur Hasan: We have done lots of probiotics studies, which are very strain-specific.
#MBCongress2019
@CosmosID Nur Hasan: We have developed large curated strain-level databases @CosmosID , and I invite everyone to try our tools online at app.cosmosid.com
#MBCongress2019
@CosmosID @threadreaderapp bring on the unroll
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