Michael L. Barnett Profile picture
Jun 3, 2019 13 tweets 14 min read Read on X
New work in @AnnalsIM, presentation at #ARM19 tomorrow

How hard is it for those with opioid use disorder (OUD) to find a buprenorphine prescriber in states with the worst overdose burden?

w/ @tamarabeetham @DrSarahWakeman @BrendanSaloner + Marema Gaye

annals.org/aim/article-ab
@tamarabeetham @DrSarahWakeman @BrendanSaloner @AcademyHealth @HarvardChanSPH @HarvardHPM @JohnsHopkinsSPH First, a poll before I share results:
What is your best guess for the average wait time to get a new appointment with a buprenorphine prescribing in states with a high burden of OUD (e.g. WV, OH, MA, NH)?
@tamarabeetham @DrSarahWakeman @BrendanSaloner We did a “secret shopper” survey: 1,092 calls to 546 publicly-listed prescribers in WV, OH, MD, DC, MA and NH posing as people using heroin looking to restart buprenorphine.

Two calls to each prescriber – once as Medicaid-insured, once as uninsured/cash pay.
@tamarabeetham @DrSarahWakeman @BrendanSaloner Outcomes we tracked:
1) New patient acceptance
2) Possibility of getting buprenorphine at 1st visit without delay
3) Wait time to 1st appt
4) Cost of appt for uninsured
@tamarabeetham @DrSarahWakeman @BrendanSaloner We got a response for 78% of our calls, covering 81% of in-sample prescribers.

Depressing initial result – half of all calls using SAMHSA public listings were erroneous, no longer active, wrong clinical setting (e.g. emergency room)

Big initial barrier to finding a prescriber
@tamarabeetham @DrSarahWakeman @BrendanSaloner Key results:

New appointments:
- 46% of prescribers not accepting new Medicaid patients
- 38% not accepting new cash pay patients

Possible induction on 1st visit:
- 27% of contacts offered appointment with possible bupe at 1st visit for Medicaid
- 41% for uninsured/cash-pay
@tamarabeetham @DrSarahWakeman @BrendanSaloner Despite high rates of rejecting new appts, wait times were surprisingly short when we actually reached a clinic taking new patients:

Median wait time 5-6 days (!) among those offering appts

Consistently low wait time across all subgroups
@tamarabeetham @DrSarahWakeman @BrendanSaloner What about cost?

Median cost until induction - $250

5% of prescribers charge over $500

54% of prescribers said there were unknown add’l fees for urine/lab testing
@tamarabeetham @DrSarahWakeman @BrendanSaloner Other observations:

Variation at state level
- Biggest Medicaid/uninsured disparity in access in NH and OH
- MA had lowest rate of prescribers offering possible induction

Best appointment availability among NP/PAs, 275-waivered MDs

Lower availability in rural areas
@tamarabeetham @DrSarahWakeman @BrendanSaloner Takeaways
1) It takes a lot of phone calls to find someone who might actually offer an appointment
2) Maybe because it’s so difficult, wait times are short among those taking patients
3) Disparity in rapid induction between Medicaid/cash pay: Medicaid formulary barriers?
@tamarabeetham @DrSarahWakeman @BrendanSaloner Policy implications
1) Need interventions to better match pts to prescribers who are open
2) Maintaining an accurate online prescriber directory should not be not that hard, why don’t we do it?
3) Medicaid programs need to pay more/reduce barriers to close disparities in access
@tamarabeetham @DrSarahWakeman @BrendanSaloner Enormous thanks to my wonderful and talented team.

Especially for @tamarabeetham, who accomplished something remarkable leading this study while getting her MPH. Her effort got this work a best abstract award at #ARM19!!!!

More to come in this space
@tamarabeetham @DrSarahWakeman @BrendanSaloner Also read the very thoughtful editorial with points I didn't think of by @PoojaLagisetty @Amy_Bohnert

annals.org/aim/article-ab…

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More from @ml_barnett

May 10, 2023
New @NEJM out today!!

After a high risk OUD event (OD or detox)
- White patients get buprenorphine 80% more often than Black pts
- This is not due to diffs in methadone or frequency of health care access
- Rates of rx opioids/benzos are HIGHER than bupe

nejm.org/doi/full/10.10… Image
@NEJM Before I dive in, this was a joint effort of @HarvardHPM @HMSHCP @DartmouthInst w/ Nancy Morden, @ermeara @Ateevm @DrLewinson and many others

We focused on disabled Medicare enrollees from 2016-2019 with an OUD "index event" like OD, IV drug related infection or detox/rehab. Image
@NEJM @HarvardHPM @HMSHCP @DartmouthInst @ermeara @Ateevm @DrLewinson We captured a high risk pop with a clear "touchpoint" (h/t @MarcLarochelle) indicating severe OUD. The need for treatment is obvious and shouldn't vary much by race, right?

Nope. White pts got buprenorphine 23.3% of the time compared to 18.7% and 12.7% for Hispanic and Black pts Image
Read 12 tweets
Mar 23, 2023
Excited to share a new paper today with @McGarryBE and @ashdgandhi published today in @NEJM

TL;DR Nursing homes with higher use of COVID-19 tests for staff had 30% fewer resident cases and 26% fewer deaths than low testing facilities. That's a LOT.

/1


nejm.org/doi/full/10.10… Image
@McGarryBE @ashdgandhi @NEJM Why does this matter? In the early pandemic, we had no vaccines, no Paxlovid. Top priority - keeping COVID out of nursing homes by testing staff frequently. But a lot of nursing homes didn't.

We need to understand what this policy failure cost us.

/2


washingtonpost.com/health/2020/09…
@McGarryBE @ashdgandhi @NEJM This is tricky to study because the best predictor of nursing homes testing more is a COVID outbreak.

We got around this by developing a "relative testing rate" for each home, based on how much it tested staff vs. other homes in the same county and week.

/3 Image
Read 13 tweets
Dec 30, 2022
It's that time again - my list of 10 of the most thought-provoking, surprising, and rigorous studies in health care in 2022!

Themes this year:
1) Care delivery changes that work (and don't)
2) Race and health care
3) Natural experiments in the ED
+ a few misc. cool papers Image
Before we dive in - this list is
A) not comprehensive
B) not presented in any particular order
(I’m also focusing on papers written by folks outside my circle of colleagues/collaborators)

First up is a set of 4 studies on changes to care delivery or coverage.
#1: A lot of interventions that "feel" like they should work have not panned out.

A prime example is a very rigorous RCT to improve birth outcomes among Medicaid enrollees in SC published in @JAMA_current led by @maggiemcconnell + Kate Baicker

jamanetwork.com/journals/jama/…
Read 25 tweets
Feb 4, 2022
New work in @JAMA_current today - who has been getting those precious monoclonal antibody infusions for COVID-19 in the US?

It's not pretty ...

Work led by @CarolineLBehr with @kejoynt @ermeara Arnie Epstein and John Orav.

jamanetwork.com/journals/jama/… ImageImageImage
@JAMA_current @CarolineLBehr @kejoynt @ermeara We identified 1.9 million cases of COVID-19 in Medicare claims without hospitalization/death in the first week.

In nearly every case, those at higher risk of dying from COVID-19 were LESS likely to get monoclonal antibodies (mAbs).

jamanetwork.com/journals/jama/…
@JAMA_current @CarolineLBehr @kejoynt @ermeara Overall, 7.2% of Covid cases got mABs.

But the variation by demographic group is extreme.

0 chronic conditions: 23.2%
6+ chronic conditions: 4.7%

No Medicaid: 8.1%
Medicaid eligible: 4.6%

White: 7.4%
Black: 6.2%

No dementia: 7.8%
Dementia: 3.7%
Read 6 tweets
Dec 22, 2021
Here's my list of 12 papers in 2021 at the intersection of health care, medicine, economics and policy that surprised me, made me think, or were just damn clever.

I'm just going to focus on non-COVID-19 papers - we have enough of that other stuff in our feeds.

Off we go!

/1
Before we dive in - this is
A) definitely not comprehensive
B) definitely not in order of awesomeness

I’m also focusing on papers written by folks outside my direct circle of collaborators (w/ a couple of non-Harvard exceptions I can’t resist).

Sorry @AnupamBJena

/2
@AnupamBJena The first set of papers falls under the theme of "obviously broken systems that we could fix and improve health."

Paper 1:
"SNAP Participation and Health Care User in Older Adults" led by Seth Berkowitz @UNC_SOM and @SanjaybMDPhD in @AnnalsofIM

acpjournals.org/doi/10.7326/M2…
Read 30 tweets
Dec 9, 2021
New analysis in @NEJM today with coauthors @McGarryBE @ashdgandhi @DavidCGrabowski

Vaccine mandates continue to be controversial, including in nursing homes. What are the stakes exactly?

The results are sobering, to say the least ...

nejm.org/doi/full/10.10…
@NEJM @McGarryBE @ashdgandhi @DavidCGrabowski From June-Aug 2021, we compared resident and staff infection + mortality rates between 12,000 homes with the lowest staff vaccination rates (~30%) vs. highest (~80%).

In the least vaccinated homes:
+132% COVID cases in residents
+58% staff cases
+195% resident mortality

yikes
@NEJM @McGarryBE @ashdgandhi @DavidCGrabowski Over an 8 week period, if all nursing homes were magically raised to the highest staff vaccination levels nationally (~80%), we would have:

4,775 fewer resident cases
7,501 fewer staff cases
703 fewer resident deaths (nearly 50% of all deaths)
Read 4 tweets

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