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1/ #Melatonin

The presence of melatonin in Alphaproteobacteria & 
Cyanobacteria indicates an early appearance of this multifunctional #Serotonin
derivative in the evolution of life
2/ #Melatonin

The discovery of antioxidative properties of melatonin is consistent with an ancient role of this molecule in contributing to survival under high oxygen levels or exposure to UVR.
3/ #Melatonin

Because of melatonin production in mitochondria scavenging of free oxygen radicals has likely been a primary role of melatonin in evolution originating around 2.5–3 billion years ago
4/ #Melatonin

In all organisms, melatonin is formed from tryptophan via serotonin.
In vertebrates, melatonin is mainly perceived as the hormone of the pineal gland.
5/ #Melatonin

The mammalian pineal gland represents the major source of melatonin in the blood, & in the cerebrospinal fluid of the third ventricle of the brain, where it contributes to the regulation of the circadian system
6/ #Melatonin

The amount of CIRCULATING melatonin is relatively the same across all races.
7/ #Melatonin

Melatonin controls pigmentation changes by aggregation of MELANIN into the melanocytes within the skin, causing the skin to change color.
8/ #Melatonin

This interaction is also responsible for the paler skin color of elderly people and those with insomnia.
10) #Melatonin

Melatonin is being looked at for #AntiAging & possible #LifeExtension properties

ncbi.nlm.nih.gov/m/pubmed/24112…
11) #Melatonin

Where have we seen this before?
👇

science.howstuffworks.com/innovation/sci…
12) #Melatonin

Currently, #Melatonin is MORE VALUABLE than #GOLD
13) #Melatonin

Many beneficial properties

sciencedirect.com/science/articl…
14) #Melatonin

But, where does it fall in the #RedTrade ..?
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