Dr David Robert Grimes Profile picture
Aug 16, 2019 15 tweets 10 min read Read on X
Look what just arrived! Really strange sensation to be holding your own book, but here we are! "The Irrational Ape" is out Sept 5th, on why we get everything from medicine to politics wrong - & how we can fall stop ourselves falling victims to fools, liars, & charlatans..
Is it terribly self-indulgent to tell you a little about it? Because I really want to, but don't want to spam people. But figure if you follow me, you're probably familiar with elements of my oeuvre, but this is a little different..
I'll try to distill it - for years, I've been fascinated by how we get things wrong. Despite having powerful inferential brains, we frequently make mistakes that cost us dearly. In an age where misinformation abounds, we've never been more at mercy of dangerous falsehoods..
..there's so many avenues for error. We can be misled by the veneer of illusory logic, bamboozled by rhetoric, & lied to by numbers. Our own psychological biases can skew our reasoning completely, & the media we consume both online & off shapes our perception markedly..
..in "The Irrational Ape", I've delved into all these aspects, with real bizarre stories from throughout history from the comical to the catastrophic. The book has murderous popes, snake-oil salesmen, esoteric cults, superstitious pigeons, fraudulent psychics, cold war politics..
.. satanic panic, unethical doctors, vaccine cranks, courtroom drama, religious fantatics, conspiracy theorists, and a few narrowly averted cases of Armageddon. And in each story, a exploration of what went wrong. Things like this..
Most importantly, I try give a schema we can all use to avoid becoming victims to nonsense & disinformation, & show how we can all use critical thinking to improve not only our own lives, but the world itself. This is so urgent now, when falsehoods perpetuate without bound
Anyway, I really hope you enjoy it. It's out September 5th, & pre-order details in the tweet below. It's also on audiobook narrated by muggins here, & I've done an interview with @audibleuk you can see soon!
There's also so many people I have to thank, but maybe I should save that for a little later, as it could be a long thread. But right off the bat, @robinince has been a complete gentleman & I am deeply grateful to him for both the support & lovely quote.
Actually, I think I should at least briefly thank some of the people to whom I owe a lot - @SLSingh encouraged me to write, & put me in touch with my wonderful agent @Walsh_e_Patrick - I also need to thank my editor @IanPlayfair & also @John_S_Ash for their invaluable input..
..I also need thank @RichardDawkins who gave his valuable time to check my facts on Darwin, and for his excellent insights. I also am indebted to @DrRobertOConnor @gorskon @susmitchellSBP @TheresaNewIdea @ciarakellydoc @MrMMarsh & @donalb5 among others..
..My family also played a big role in getting this over finish line - but especially, I want to focus on the people to whom the book is dedicated; @Mathild_HpsyC @MrDannyMurray & @laura_jbrennan - without their support, affection, & encouragement this book wouldn't exist.
..as many of you know, @laura_jbrennan was a courageous & brilliant campaigner for the HPV vaccine. She passed away in March, so there's something a little bittersweet about all this. Without her, I'd never have finished the book - her story is in it, her influence on every page.
Anyway, I'll stop babbling. There's loads of people I've missed thanking due to my own thoughtlessness but I'll do a proper thread on it in the near future - please forgive me if I skipped a name here. Thanks for reading, I hope you enjoy.

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More from @drg1985

Jan 30
Social media plagued by health grifters, scaremongering, & snake-oil peddlers, many with huge followings. I'm often asked to weigh in on claims and confirm whether someone is a pushing misinformation or not. Here's a useful heuristic for spotting health charlatans.. a🧵.. Image
..First question: Does claimant have relevant experience? Have they related qualifications, publications, or specific expertise to assess and make the claim they do? If not, that is a red flag. Also, important to dig beyond appearance: any grifter can pose in lab coat or scrubs Image
..Second question: Are they extrapolating from limited evidence, or dubious sources? Murine studies and petri dish prelims should never be the basis for human health advice. Also be extremely wary of someone who takes a small study, or a weak association, and makes a big claim Image
Read 8 tweets
Jan 26
Whenever I see a guideline insisting we're all Vitamin D deficient, I get a sinking feeling I'm reading the legacy of bad science. Meta-scientists often complain how Vitamin D research is, as a field, so methodologically shabby as to be meaningless. How bad? Well let's dig in...
Firstly, what *is* vitamin D deficiency? Methodologists say not to dichotomise a continuous variables for good reason, & medical scientists completely ignore this because they want pretty results. I looked at last 5 years of Vit-D obs. trials: Here's what it looked like.. Image
..you read that correctly. Of trials that set an arbitrary threshold (the majority), authors used at least 9 different thresholds, ranging from 0.2 ng / mL to 200,000 ng / mL. Generously assuming they're howling typos, 20 ng / mL was most common, then 10 ng/ mL, then 30 ng / mL
Read 15 tweets
Jan 1
Misinformation, disinformation and malinformation are rampant on social media, and their influence and prevalence will only get worse in 2024. I'm often asked what we can do to limit their harms. Here are some simple suggestions. A short thread 🧵 Image
..first, we need distinguish between them. Misinformation is the inadvertent sharing of falsehoods, disinformation is the deliberate propagation of the same, and the lesser-known cousin malinformation is the weaponisation of information out of context to mislead. All are harmful Image
So what can we do to protect ourselves? First and foremost, we can check our sources. When we come across a claim, we need to determine whence it originates and its inherent veracity. Is it fact-checked, or from a reliable news source? Or does it come from a dubious corner? Image
Read 11 tweets
Jun 18, 2023
So @joerogan insisting @PeterHotez "debate" notorious antivaccine spoofer RFK Jr shows Rogan fails to grasp debate is only useful if conducted in good faith. If one party lies, youre just giving them a vehicle to spread that lie to detriment of understanding. A short thread.. 🧵
So debate is not an arbiter of truth. If one perspective amply supported by evidence, & another completely unsupported, giving them equal consideration merely because theyre opppsed has effect of allowing the unevidenced view leech an illusion of legitimacy, misleading people
...this is the false balance problem, and it has utterly damaged public understanding on everything from climate change to vaccination. Cranks adore it, because it allows them to push their misinformation, as I wrote for guardian in 2016

theguardian.com/science/blog/2…
Read 9 tweets
Mar 29, 2023
Good grief - utter nonsense shared yesterday by @ABridgen and his ideological cohort claims COVID vaccines are dangerous has gotten huge traction, but its founded on an utter abuse of data. Let's look at precisely why its junk - Strap in, it's a thread... 🧵 Image
..firstly the source is Expose News, which solicits donations & pumps out conspiracy junk. They've taken publicly available ONS data, and presented it as shocking: for example, this is their figure (mislabelled as it is) of unvaccinated versus vaccinated deaths April-Dec 2021... Image
..4034 deaths in unvaccinated versus 13,116 (~76.5%) deaths in vaccinated cohort, scary right? Well.. no: in the same period of time, 93.6% of UK were vaccinated; so a tiny fraction of unvaccinated (6.4%) accounted for 23.5% of deaths, 3.7x greater hazard being unvaccinated! Image
Read 9 tweets
Mar 3, 2023
US Department of Energy (DoE) report on COVID origins & FBI director on Fox news has set cat among pidgeons again -so is a #lableak now more likely now?

No - and demands to investigate lab-leak narratives neglect basic principles of scientific inquiry; a thread 🧵 Image
So first thing to note is the DoE report is classified, but concludes with "low confidence" - what does that mean in practice? That its unreliable, and not a basis for an analytical conclusion. Note that the report didn't change any other intelligence outfits minds either.. Image
This togethers implies that any ostensible evidence DoE marshal is somewhat underwhelming; not surprising when steady evidence has accumulated since 2020 all pointing to the conclusion that the virus emerged from animal spill-over, with not a shred of solid evidence otherwise..
Read 15 tweets

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