Thread by @KarlZelik

New #prosthetics publication that came out during @ISB_ASB2019 characterizes how individual prosthesis user gait biomechanics were affected by the next-generation @OssurCorp Propriofoot (ankle adaptation to slope) during incline walking. 1/n

sciencedirect.com/science/articl…

@ISB_ASB2019 @OssurCorp Previous studies on similar microprocessor-controlled ankles have focused on group-level results (inter-subject mean). Our study builds upon this by presenting subject-specific results and investigating to what extent individual responses agree with the group-level results. 2/n

@ISB_ASB2019 @OssurCorp The ProprioFoot increased minimum toe clearance for all subjects. Despite the ankle behaving similarly for each user, we observed marked differences in individual responses, e.g., intersubject differences in landing patterns, center of pressure (COP) knee angles and moments. 3/n

@ISB_ASB2019 @OssurCorp Individual user responses were often not well represented by group mean. Prevailing experimental paradigm in prosthetic gait analysis is focused on group results, but our findings call attention to high inter-subject variability which may necessitate other experiment designs. 4/n

@ISB_ASB2019 @OssurCorp I noticed several other presentations/posters @ISB_ASB2019 which also broached a similar methodological topic and this question about #biomechanics study design, and subject-specific interventions or evaluations. 5/n

@ISB_ASB2019 @OssurCorp Particularly for studies on new/emerging tech. I'm currently reflecting on pros/cons of alternative study designs (e g. single-subject design), analyses, outcomes & data visualization methods. Input welcomed on how others are thinking about tackling these challenges... 6/n

@ISB_ASB2019 @OssurCorp Also thinking about why group-level analysis (t-tests, ANOVAs) seems to have become the de facto standard in #gaitanalysis studies, specifically #prosthetics research; given the well-known heterogeneity of persons with amputation & variability in response to interventions. 7/7

Lead authors on this research were @lamers_erik and @EveldMaura