Cholesterol is so important for brain health that the brain has its own synthetic machinery for making it.
The brain is only 2% of body weight yet contains as much as 25% of the body's cholesterol.
Blood levels of total and LDL cholesterol are lower in Parkinson's disease patients.
Ferritin (iron) levels are higher.
[PMID: 21282940]
Some statins, those that are lipophilic, can penetrate the blood brain barrier.
The effects of these statins has been described as "pleiotropic", meaning they do lots of things; since they lower cholesterol, presumably many of these things are not good.
The well-known negative correlation between water hardness and atherosclerotic heart disease can be explained almost entirely by lithium levels.
The inverse association of water hardness and cardiovascular disease has been found in many countries.
Psychiatric patients taking lithium had massively lower rates of seizures, AML, dementia, and heart attack, compared to psychiatric patients not taking lithium.
1. High blood pressure (without meds) 2. A1C over 5.6% without meds 3. HOMA-IR above 1.4 4. Triglycerides / HDL over 2 5. Overweight or obese BMI 6. High body fat % 7. Waistline > 50% of height
High blood pressure without meds:
While there is a genetic component, the root cause of high blood pressure is related to your weight and especially body fat %.
A1C higher than 5.6% without meds:
This one is easy to explain: once you get to an A1C of 5.7% or higher, you get into the pre-diabetic range.