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Suzanne Fustolo-Gunnink Profile picture
@FustoloSuzanne
Oct 26, 2019 • 3 tweets • 3 min read • Read on X
100 followers!😊 Thanks @MaartenvSmeden for introducing me to twitter. Time for a quick intro. I am an MD who also trained as clinical epidemiologist @LUMC_Leiden. I recently finished my phd in neonatal hematology (defense Jan 31st) @UvA_Amsterdam @amsterdamumc 1/3
Topics: platelet tx, @PlaNeT2_trial, SR, prediction, propensity, HTE). Great team of phd supervisors: @KDraat (pediatric hematologist), Enrico Lopriore (neonatologist), Anske vd Bom (epidemiologist) and Simon Stanworth (hematologist). I am Dutch, married to an Italian-American.
Mom of a boy (3 yr) and girl (3 months). Recently started as a postdoc @sanquin, again in neonatal hematology (#neohematol) Thanks for following, will try to keep you updated on this topic. And thanks for teaching me on other topics as well, learning lots from my twitter feed!

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More from @FustoloSuzanne

Suzanne Fustolo-Gunnink Profile picture
Sep 21, 2020
Lots of variation in practice in this poll looking at prophylactic platelet transfusions for preterm neonates. What’s the evidence? @Atul_Monash suggested a tweetorial, which is a first for me, but here we go. 1/13
We give platelet transfusions to preterm neonates to a) treat bleeding or b) prevent bleeding (prophylaxis). Most transfusions are prophylactic. Do they reduce risk of bleeding? Up until the @PlaNeT2_trial, no one knew. doi.org/10.1182/blood-… and sciencedirect.com/science/articl…
The only previous trial by dr. Maureen Andrew and her group was published in 1993 and compared a threshold of 50x10^9 vs 150x10^9 which is higher than currently used in clinical practice. There was no difference in IVH rates between the 2 groups. doi.org/10.1016/S0022-….
Read 14 tweets
Suzanne Fustolo-Gunnink Profile picture
May 13, 2020
Are you a neonatologist, hematologist, transfusion expert, epidemiologist or statistician and interested in neonatal transfusion research? Contact me and join a neonatal transfusion network in-the-making. Trainees and ECR welcome. @EBNEO @blooducation #epitwitter #statstwitter
I forgot to mention a very important group: fundamental researchers are also invited to join.
Wow, lots of response. Perhaps good to clarify that we will have quite a strong focus on Europe, but ofcourse are open to participants from all over the world.
Read 4 tweets
Suzanne Fustolo-Gunnink Profile picture
Oct 25, 2019
2dary analysis of @PlaNeT2_trial out now. @KDraat @ESteyerberg @Willem_Pieter @BloodJournal #ebneo #FOAMneo #neohematol . A thread. Primary result of trial: more bleeding/death in neonates treated acc to prophylactic platelet tx threshold of 50 comp to 25. 1/3
We reanalyzed the data to look for subgroups of neonates that might benefit from the 50 threshold after all. Instead of using conventional subgroup analyses we used a more robust predicted baseline risk approach. More info? Start reading here: doi.org/10.1136/bmj.k4… 2/3
We did not identify subgroups that benefit from the 50 threshold, though model needs further improvement. Suggests prophylactic platelet tx threshold of 25 appropriate for all preterm neonates, incl those at high risk of bleed/mortality. 3/3 @sanquin @LUMC_Leiden @amsterdamumc
Read 4 tweets

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