Karl Zelik Profile picture
Dec 4, 2019 14 tweets 7 min read Read on X
One of the most common questions I hear is: could occupational #exoskeletons cause muscle atrophy/loss? Interestingly I’ve never heard anyone ask: when workers develop overuse injuries (& miss work for days, end up immobilized for weeks, or leave) does it cause muscle atrophy?
1/
I’m far more concerned about the latter scenario, which we know occurs regularly. Based on current scientific evidence, given the modest unloading provided by most #exoskeletons & #exosuits, & given the strenuous jobs done by industrial users, atrophy seems unlikely (imho).
2/
Relevant excerpt from Krogh-Maden et al. in the Journal of Applied Physiology:
“...most literature suggests that reduced muscle loading must be drastic, such as limb immobilization or bed rest, to observe muscle atrophy."
physiology.org/doi/full/10.11…
3/
Also here’s a great figure from a publication on skeletal muscle properties. It shows that far too little or far too much muscle activation can lead to atrophy. But for a large intermediate range of activations muscles maintained their mass (i.e. did not atrophy).
4/ Image
Individuals in physically demanding jobs often work 8 to 10+ hour shifts, in addition to physical activities they do at home. Many are already over-exerting themselves (over-stimulating/activating muscles) on a daily basis.
5/
Hypothetically, if we were to map the physical demands of these jobs onto that muscle mass vs activation figure, then I'd expect to be in the middle or over towards the right side of the plot…
6/
...maybe even on the right-hand descending portion of curve for some workers/jobs, which suggests that occupational #exoskeletons & #exosuits that unload muscles might actually lead to increased muscle mass (hypertrophy) and prevent atrophy.
7/
While I understand why people ask "could exoskeletons cause muscle atrophy?", I believe we should also be asking the opposite: "could #exoskeletons prevent/reduce muscle atrophy?" E.g. by reducing injuries & missed work, or empowering an aging workforce.
8/
For those who haven't worn an exoskeleton yet… it's not like being bedridden, immobilized or launched into space for a prolonged time. The vast majority simply provide partial assistance during physically onerous tasks; for example making a heavy object feel less heavy.
9/
It may initially seem counterintuitive, but scientifically it seems completely plausible (and I'd say probable) for occupational #exoskeletons & #exosuits to combat rather than induce muscle atrophy in the long run, in a variety of circumstances and applications.
10/
#Exoskeletons are an emerging field & we are excited to learn more about longitudinal effects on users as more devices become adopted into industry, and are viable to use/study over months and years.
11/
In the meantime, its valuable to remember that these technologies are built upon & benefit from a wealth of knowledge from fields like musculoskeletal #biomechanics, material science & #ergonomics, which provide insight on what to expect from exos & other assistive tech.
12/
Hope these thoughts are helpful in broadening and balancing the conversation around #exoskeletons and #exosuits, and their effects on musculoskeletal health. Exciting times ahead for the field!!
13/13
Update: this Twitter thread turned into a Forbes article thanks to @ExoskeletonRep
forbes.com/sites/borislav…
#exoskeleton #exosuit #supersuit #biomechanics #WearableTech #wearables

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More from @KarlZelik

Jun 3, 2023
Exoskeletons in construction:

Nice article posted to the Associated Builders & Contractors of Wisconsin website & co-written by Prof. Zhenhua Zhu from UW-Madison & Mariya Sorenson, a construction manager with M.A. Mortenson.

They highlight 3 potential broad impacts of exos: Image
1. Improving worker safety & fostering a better safety culture in the construction industry.

Exoskeletons can reduce fatigue, muscle strain & wear-and-tear injuries, which could lead to substantial cost savings.
2. Alleviating the shortage of skilled construction workers.

Exoskeletons could help extend careers & attract candidates who might otherwise be deterred by physically demanding jobs.
Read 7 tweets
May 31, 2023
🚀 5 years ago, I stumbled—somewhat unexpectedly—into the world of tech translation, commercialization & startups. It's been a wild & enriching adventure!

👨🏾‍🔬 As a scientist-turned-entrepreneur, this journey opened my eyes to the business world.

But...
😡 Amidst all the positive learning & growth, there's one thing that truly gets under my skin: misleading marketing & unsubstantiated claims.
😬 Brace yourself: The wearable & assistive tech industry (think #exoskeletons, #prosthetics, sensors) is still plagued by this problem! Whether it's in clinical, occupational, sport, or recreational applications, we need to address it head-on.

Now...
Read 11 tweets
Nov 16, 2022
I spend a lot of time thinking about & discussing the science of #exoskeletons.

3 years ago, the single most common question I heard was:

❓Do exoskeletons cause muscle atrophy?

Short answer: No.

But I don't hear this as often anymore.

I believe there are 2 reasons why👇🏽
1️⃣ Science Communication

• For a long time, exo engineers/scientists mostly spoke to each other

• But now a broader audience is interested in exo tech

• And more researchers/developers are engaging in public discourse

This is helping reduce exo myths & misconceptions 👏🏽 🎉
If you want a quick rundown on:

• what causes atrophy (muscle weakening/wasting)

• why exos are more likely to prevent atrophy than to induce it

Then check out this thread:
Read 7 tweets
Nov 15, 2022
Where do your research ideas originate from?

I used to source all of mine from academic literature & conferences, or from my own research.

But these can become echo chambers that limit thinking & creativity.

🔥 Here are 4 overlooked places to find impactful research problems:
1️⃣ Your own life

• This is why I started studying low back #biomechanics
• I was a parent to young kids & experiencing back pain
• I was curious if we could create more practical exoskeletons that'd fit into my own life

It started as an undergrad project then grew into more:
2️⃣ Spending time w/ users

• In academia we often talk about this
• But we tend to involve users too late in R&D
• And I'm not convinced we spend enough time doing it

Hearing pain points directly from #prosthetics users is what prompted the daily activities we now study:
Read 6 tweets
Oct 15, 2022
Science is the foundation, but user feedback is the north star:

• to know what to prioritize
• to learn where to improve
• to remember why you sweat all the science details

This is a vital lesson for those doing applied research whose feedback is mostly from other scientists
The combination of #biomechanics science and user-centric design is beginning to have the real-world impact the occupational #exoskeleton field long hypothesized it would.

End-users explain this best:
“When you show you care about people, that retains people,” one warehouse worker who piloted a back exosuit said. “Everybody in here, we’re all sore. We’re all hurting. But for the first time in a long time I won’t be hurting walking out of this building [because of the exosuit]”
Read 4 tweets
Oct 14, 2022
Early career researchers often stress out when they talk to more senior faculty about how many grant proposals they submit.
 
Don't compare. Focus on your writing process. Outcomes will follow.
 
Here are 5 proven tricks senior faculty use to submit more high-quality proposals:🧵
1. Resubmitting

• Revise/resubmit an unfunded proposal
• This takes much less time than writing a new application

This is easier to do (and comes naturally) as you get further into your career.
2. Repurposing

• Take a similar core idea and apply it to a new population or context
• Or you can sometimes submit the same proposal to multiple agencies (check w/ program officers first; you just can't accept two grants for the same work)

This helps get more shots on goal.
Read 7 tweets

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