I know giving q4h penicillin G for a viridans group streptococcus endocarditis feels very classic and elegant, but man is it ever awful for the patient in hospital. They can’t go anywhere because they’re getting antibiotics so often! #IDDailyPearl
So here’s my food for thought question: assuming we don’t do oral treatment, and given that endocarditis is actually pretty rare, why don’t we give ceftriaxone rather than Pen G given the inherent issues with the latter? I’m only meaning to spark discussion. No agenda :)
It’s good stewardship bcz there little ecologic effect treating a rare entity. Less problems with PICC blockage. Easy to give daily dosing. Better quality of life for patient for time you’re giving it. No need for dosing acrobatics. No renal adjustment. Easy to remember dose.
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