IBCC correction: Procalcitonin in COVID-19 π¬. Initially the IBCC stated that COVID-19 didn't generally increase procalcitonin, based on several studiesπ... but intubated COVID patients in my unit are routinely showing procalcitonin elevations in the range of 1-10 π€ #MeaCulpa 
if we dig deeper into the Guan study, we see that some patients with more severe disease *do* have procalcitonin elevation π. so procalcitonin elevation might be a reflection of more severe infection, vis a vis cytokine storm π©οΈ.
(study: bit.ly/2vPTyWq)
(study: bit.ly/2vPTyWq)
π recent meta-analysis of procalcitonin in COVID-19 also found this: elevated procalcitonin may be a marker of more severe disease. (although can't prove with 100% certainty that these patients don't have bacterial co-infection)
(article: bit.ly/2QLk8Y2)
(article: bit.ly/2QLk8Y2)
summary on procalcitonin & COVID-19
π§ͺ COVID can β¬οΈ procalcitonin (esp severe dz)
π§ͺ Procalcitonin can't sort out bacterial infection vs. COVID
π§ͺ Currently no evidence-based role for procalcitonin in COVID dx (π₯ makes me sad)
(IBCC section: bit.ly/2JeBCaS)
#COVID19foam
π§ͺ COVID can β¬οΈ procalcitonin (esp severe dz)
π§ͺ Procalcitonin can't sort out bacterial infection vs. COVID
π§ͺ Currently no evidence-based role for procalcitonin in COVID dx (π₯ makes me sad)
(IBCC section: bit.ly/2JeBCaS)
#COVID19foam
β’ β’ β’
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