This week, NBTC released an updated Red Cell Shortage Plan. Why is it needed and what does it say? Keep reading for some #blooducation@PBM_NHS
Blood donation levels are falling consistently due to reduced donor activity. At the moment, blood stocks look good because elective work has ceased in most hospitals and NHSBT are working to increase donations. But it is anticipated soon demand will exceed supply.
Every hospital needs an Emergency Blood Management Plan in order to respond to notifications from @NHSBT. There are 3 phases;
•Green: supply meets demand
•Amber: Reduced availability of blood for a short or prolonged period
•Red: Severe, prolonged shortages
NHSBT aim to keep 6 days of stock for red cells.
At how many days’ stock does NHSBT issue the amber alert?
The amber alert is issued at 2 days’ stock. This means that stocks are already significantly reduced at this point.
To whom is the alert issued?
The alert comes to the transfusion laboratory manager
Amber/Red can be called on
The amber or red phase can be called on any group, any component. Most commonly it is called for A neg platelets and O neg red cells
When the amber/red phase are called the emergency blood management group should be convened. This group needs representation from the medical director, operational and risk management, key clinical users and the hospital transfusion team.
The EBMG provides strategic guidance and makes arrangements to manage appropriate use of blood in each operational phase. It is essential that the EBMG have senior hospital management support i.e. from the Chief Executive and Medical Director to ensure their effectiveness.
They, or a key group of individuals, should meet daily during shortages to review necessary actions
Suggested measures for preserving stocks: amber (most hospitals are already doing these)
•Review transfusion triggers
•For pts w high needs, liaise with lab/haem cons
•Reduce reservation period
•Consider temperature loggers in boxes to reduce wastage
•Reduce stock
Preserving stocks: red phase
•Review stock levels
•All requests for blood components to be reviewed by lab/haem cons to minimise inappropriate requests
•Remove red cells from remote fridges, except flyers
All changes to be communicated to clinical and management teams
NHSBT have plans to increase supply at times of shortage, such as calling more donors, extending working hours of manufacturing and donor sessions, increasing monitoring and mobilisation of stock around the country. These measures are already taking place.
During shortages NHSBT will monitor blood usage in hospitals. Where hospitals are unable to meet the recommended reductions in stockholding and use, the haematologist or laboratory manager will be expected to discuss with an NHSBT consultant, or PBM practitioner.
When returning to green it should be remembered that increase in elective work may place further demand on blood supplies.
This was a quick run through the EBMG. How prepared are you? Do the relevant people in your trust know their roles? Easter will be a particularly challenging time, especially for platelets. Make sure you are prepared!
I had a personal request to do a tweetorial for the #haemSpRs on haemovigilance. Here goes. A #blooducation 🧵
Haemovigilance is a systematic surveillance of adverse reactions and adverse events related to transfusion’ with the aim of improving transfusion safety. transfusionguidelines.org/transfusion-ha…
We are very lucky in the UK to have @SHOTHV1, one of the first in the world to collate adverse events relating to transfusion - since the 1990s.
This morning I met with the chair and vice chair of the Midlands Regional Transfusion Committee, the Midlands Patient Blood Management Practitioner and the Customer Services Manager. What are their roles and what does the RTC do?
A #blooducation 🧵
RTCs serve to bring together Hospital Transfusion Committees to discuss best practice, implement new guidance and provide educational resources and events. They are run by clinicians and scientists working in hospitals, supported by @NHSBT.
Teaching our incoming haematology doctors today about transfusion in haematology patients. So who needs irradiated blood and why? A #blooducation🧵
All blood in the UK is leucocyte reduced (except granulocytes, but that’s another story). Despite this, a unit of red cells or platelets can have around a million residual white cells, mostly lymphocytes.
Every doctor starting in a new trust does transfusion training as part of their mandatory training. But why?
50ml ABO incompatible blood can kill a patient. ABO antibodies are naturally occurring (“everyone” has them) and they are IgM; they can activate complement and cause *immediate* intravascular haemolysis, causing release of free haem, endothelial activation, renal failure and DIC.
In most hospitals, blood banks require 2 samples (one may be historic) before releasing group specific (non-O) blood for a patient. This is to increase the chances of identifying a *wrong blood in tube* (pt whose blood's in the tube is not the pt whose details are on the outside)
It can be difficult to know where to start with transfusion – you can’t go on a ward round to find patients. BUT you do start with lab induction and your helpful #BMSes will show you around.
Excellent session on emergency paediatric transfusion #AABB20. Cyril Jacquot talking on pre hospital transfusion and summarising the literature.
28 day mortality following haemorrhage is higher in children than adults (unpublished data and substudies from PROPPR and PROMMTT)
Observational studies of large numbers of patients but with only very small numbers of paediatric patients suggest that pre hospital blood is not associated with an excess of transfusion reactions and in some studies is thought to have improved survival.
Whole blood, group O, high titre neg, used in paediatrics in Pittsburgh appears to be safe with no haemolysin-mediated haemoylsis in non group O patients (Leeper et al JAMA Pediatrics 2018) ncbi.nlm.nih.gov/pmc/articles/P…