My Authors
Read all threads
Why is #asymptomatic spread important? Well today I was thinking about #polio virus. It was very #contagious, but 95% of people had no symptoms but were still infectious. About 4-5% of people had minor illness: fever, headache, nausea, vomiting, weakness. #SARSCoV2 #COVIDー19
2/ About 1-2% of people had severe muscle pain, and stiffness in the neck and back. <1% of cases resulted in #paralysis including the legs and the nerves controlling breathing and swallowing necessitating use of the iron lung #ventilators. #Polio could attack the #CNS.
3/ At its peak in 1952, more than 21,000 #Americans contracted a paralyzing form of #polio, and 3,000 died from it. Once infected, there was no treatment besides time and tending to the symptoms. Interestingly, polio mostly attacked young children under age 5.
4/ In most cases, muscle function returned to some degree, and many people who developed paralytic #polio recovered completely. That said, muscle weakness and paralysis lasting a year or more could become permanent.
Although the number of cases of #polio has decreased hugely over the last 25 years, there are still around 400 cases of polio reported worldwide every year, and 1 in 200 cases ends in permanent #paralysis…
6/ People infected with #polio could also go on to develop “post-polio syndrome” or polio-related symptoms with onset occurring anytime from around 10 years to more than 60 years after initial infection, related to the damage the poliovirus did to the #neurons.
7/ We have to consider that the hypoxia and cessation of spontaneous breathing centers in the brain, as well as reported symptoms of Guillain-Barré, loss of smell + taste, headaches, and confusion seen in #COVIDー19 could be directly related to neuroinvasion by #SARSCoV2 @NEJM
8/ We need to look ahead for treatments and solutions. But we also need to look at history for lessons we may have missed. @tmprowell @marklewismd @jeremyfaust @ASlavitt
*EBV infects B cells of the immune system and epithelial cells. Once EBV's initial lytic infection is brought under control, EBV latency persists in the individual's B cells for the rest of their life.
*HCV about 80% of those exposed to the virus develop a chronic infection, having presence of detectable viral replication for at least 6 months. Most people experience minimal or no symptoms during the initial few decades of the infection
*With HCV only 5–50% of those infected in the #USA and Canada are aware of their status. Routine screening for people between the ages of 18-79 was recommended by the United States Preventive Services Task Force in 2020.
@threadreaderapp please unroll
Missing some Tweet in this thread? You can try to force a refresh.

Enjoying this thread?

Keep Current with Erin C. Sanders, MSN, RN, WHNP-BC

Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

Twitter may remove this content at anytime, convert it as a PDF, save and print for later use!

Try unrolling a thread yourself!

how to unroll video

1) Follow Thread Reader App on Twitter so you can easily mention us!

2) Go to a Twitter thread (series of Tweets by the same owner) and mention us with a keyword "unroll" @threadreaderapp unroll

You can practice here first or read more on our help page!

Follow Us on Twitter!

Did Thread Reader help you today?

Support us! We are indie developers!

This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3.00/month or $30.00/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!