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New retrospective study from Tongji Hospital in Wuhan showing 19% fatalities in critically ill #COVID19 patients treated with low dose #hydroxychloroquine, and 47% in patients not treated with HCQ.

But I have some questions.…
Q1. No patient consent was obtained to treat patients with HCQ, even though it is an experimental drug.
But this might be OK according to local rules.
Q2. Majority of patients (77%) is listed as having a fever (blue box).
But median body temp is listed as 36.6°C (Q1-Q3 range 36.3-37.0) (top red box).
That does not sound very feverish to me.
Q3. Symptoms data in the table is listed for only 458 patients - not available for almost 100?
Body temp, pulse, etc are not fancy measurements.
It is of concern that 17% of data was not available.
Q4. Median values for the total group are all LOWER than the median values for the 2 subgroups. Is that mathematically possible? See values marked in red.
* Patients were admitted until as late as April 4
* Figure 1 shows the patient survival 60 days since admission.
* Paper was submitted to journal on April 23, 2020.
I have trouble fitting a 60-day interval between April 4 and April 23.
See my concerns @PubPeer here:…
I will also write a blog post after my conference call tonight.
Hello dearest @threadreaderapp - can you magically unroll this please?
Blog post written!

Low dose of hydroxychloroquine - but lots of questions…
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