Our final print is out for Strongyloides stercoralis Infection in Solid Organ Transplant Patients Is Associated With Eosinophil Activation and Intestinal Inflammation: A Cross-sectional Study. Thanks to @EvaClarkMD @Strongylady @karlajbautista_ @a5hi5h
academic.oup.com/cid/advance-ar…
academic.oup.com/cid/advance-ar…
We detected increased eosinophils in those infected with Strongyloides and associated with increased Strongy specific IgG. 
Strongyloides activated the innate immune response and activates the eosinophils to release their cytotoxic granule proteins. Also associated with increased Strongy IgG.
Since Strongyloides spends a significant time in the GI tract, the amount of eosinophil granule protein correlates to intestinal inflammation (measured by IFABP).
Our proposed pathway for pathogenesis due to Strongyloides stercoralis in soli-organ transplant patients. The implications are poor absorption of medication/nutrition and microbial translocation leading to potential transplant organ loss.
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