Share this page!

Enter URL or ID to Unroll

You can paste full URL like: https://x.com/threadreaderapp/status/1644127596119195649
or just the ID like: 1644127596119195649

How to get URL link on X (Twitter) App

  1. On the Twitter thread, click on or icon on the bottom
  2. Click again on or Share Via icon
  3. Click on Copy Link to Tweet
  4. Paste it above and click "Unroll Thread"!
  5. More info at Twitter Help
Ewan Birney Profile picture
@ewanbirney
Jun 19, 2020 • 4 tweets • 1 min read • Read on X
Tuning back into #NanoporeConf online and hearing thumping 70's, 80's and 90's tune in the warm up. London Calling is such a great track and now will forever be linked to hitech DNA sequencing :)
Gordon (@GSanghea) opens saying that this a sombre time with a global pandemic - but the innovation does not stop, in particular LamPORE as Nanopore's first diagnostic offering focused first on SARS-CoV-2 but in the future broader infectious agents.
Q-line is the new product line focused on diagnostics (editorial - diagnostic stuff rightly has far more regulation which makes a different beast). Q-line GridIONs are available from nanopore store today.
Has a cheesy video on the MinION Mk1c which is the combination of a sequencer, a dedicated analysis package (basecalling and primary analysis) and connectivity/control (basically - a touchscreen and user analysis). Just needs electricity - can sequence anywhere.

• • •

Missing some Tweet in this thread? You can try to force a refresh
　

Keep Current with Ewan Birney

Ewan Birney Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @ewanbirney

Ewan Birney Profile picture
Apr 2
A short, personal thread on what is odd about other cultures when interacting with Brits, and then also what I think is odd about Brits when interacting with other cultures - highly, highly personal, but from >30 years working internationally.
German+Dutch do not have to preface a challenge with "I think you might have missed something..." or some other British-style softening up. It is entirely fine - indeed polite/shows respect - just come out "you are wrong because X,Y" - this directness is surprising for a Brit.
Northern (Protestant/river/Prussian) Germans are very different from Southern (Catholic, Mountain+Forest) Germans. Don't confuse them. External stereotypes of Germans (in particular in Britain) is a weird mixture of both and you have to untangle this.
Read 20 tweets
Ewan Birney Profile picture
Feb 20
The publication of the whole genomes from the US @AllofUsResearch cohort is great to see, but the choice of how to represent an overview of the genetic relationships has (rightly) drawn controversy, in particular how the concepts of ethnicity and race are mapped to it.
This is not in bad faith - the AllofUs cohort should be applauded in its diversity push and much of the but it is an illustration of the messiness of genetics and the inability to represent our complex relationships in any 2D space. Longer thread below>>
A reminder that genetics (the variation in DNA sequence passed down from your parents, +their parents etc) and race or ethnicity (a box people tick on surveys or on census) are quite different concepts, strongly linked only by visible features which are genetic, eg, skin colour
Read 28 tweets
Ewan Birney Profile picture
Jan 19
Next monday is 4 hours of preliminary grant reviews - a necessary but intense part of being a scientist who goes through peer review is being the reviewer. As ever, I am rather amazed by scientists who make simple mistakes in their proposals. My thoughts for a good proposal:
For me as a reviewer you need to convince me of 4 major things. >>
1. Is the problem important/interesting? 2. What has changed in the last ~five years that means an important/interesting problem can now be tackled? 3. Can you actually perform the science? Is it likely to fail? 4. Why are you one of the best people in the world to do this?
Read 18 tweets
Ewan Birney Profile picture
Dec 10, 2023
It is a dark, drizzly december sunday in London and I've just read yet another depressing thread of someone reaching for genetics to justify racism and superiority to themselves. It is deeply wrong, but such a recurrent thread worth both dismantling+ understanding the attraction
Let's dismantle first; although a feature of ethnicity/race is skin colour and other visible features, and although these have strong genetic components, counter-intutively for most people, ethnicity is *not* a good predictor for genetics
(certain manipulations of genetic information are reasonable predictors of ethnicity in a single country setting but the reverse is not true; the genetic space is far more high dimensional than these crude ethnicity labels, and it all breaks down when you go global)
Read 25 tweets
Ewan Birney Profile picture
May 21, 2023
Here is the slightly cheesy montage for the great #nanoporeconf for 2023 - and, with a reminder of my conflict of interest - I am a longestablished paid consultant for Oxford Nanopore and a shareholder - here are my thoughts on the conference.
For long time nanopore scientists -and I am definitely one of those- one can definitely both plot progress London Calling conference (on the Thames in London) both in terms of what the company presents as near and long horizon+how the plenary speakers use and talk about nanopore
From the company side, much of this was giving a roadmap of key software and flow cells; the R10 flow cells (which is a distinct step up in quality) are now routine; what is not yet is high yield duplex which has being moving from Oxford to Alpha to broader Beta testers.
Read 34 tweets
Ewan Birney Profile picture
May 21, 2023
My friend and economics/ markets guru @felixmwmartin commenting on super human AI and all too human market behaviour - on the money that AI will transform many things (science included - it has started in earnest) but also more broadly in the economy
Economics and biology are closer in data science than you might think - in particular micro economics and observational human biology aka epidemiology. Plenty of differences but lots of overlap as well, eg biased sampling, many hidden confounders, clearly correlated variables
A deeper issue is the need to understand causality / intervention- if I enacted this policy or provided this drug what would happen next. Finding the golden causal threads in the tangled Gordian knot (hairball?) of correlation is a common challenge shared by biology+economics
Read 6 tweets

Did Thread Reader help you today?

Support us! We are indie developers!

This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

Send Email!

:(