Thread by @DrJonnys

Polycystic liver disease (PLD)....⤵️📚
⚜️A heriditary autosomal dominant (AD) disease.
⚜️Arises from biliary epithelium, but does not communicate with biliary system....⤵️
#SoMe4IQLatAm #SoMe4Surgery

⚜️Types:) 1ry PLD or an extrarenal manifestation of AD polycystic kidney disease (ADPKD).
⚜️Presentation: usually asymptomatic, hepatomegally, abd pain, jaundice, portal HTN.⤵️

⚜️Complications:) hemorrhage, biliary obstruction, Budd-Chiari syndrome, rarely malignant transformation.
LFTs are well preserved and so liver failure will not occur.⤵️

⚜️Investigations: US, CT, MRI.
⚕️Treatment:)⤵️
1️⃣➪:) Somatostatin analogues.
2️⃣➪:) Aspiration sclerotherapy.
3️⃣➪:) Fenestration.
4️⃣➪:) Resection.
5️⃣➪:) Liver transplantation.⤵️

#SoMe4IQLatAm #SoMe4Surgery
Treatment algorithm for polycystic liver disease subdivided by treatment goal.⤵️📚
💠Treatment is only indicated in symptomatic patients. 
💠The CT images serve to show the phenotype applicable to each type of treatment.....⤵️

💠The liver is accentuated: cysts = coloured dark & normal liver parenchyma = lighter parts.
💠Abbreviations used: AS, aspiration sclerotherapy; CT, computed tomography; PLD, polycystic liver disease; QoL, quality of life; SA, somatostatin analogues.