Sheila Vakharia PhD MSW Profile picture
Jul 10, 2020 12 tweets 3 min read Read on X
A Letter to the Editor was published in the NEJM this week by @alexhkral and colleagues summarizing their recent evaluation of an unsanctioned Safer Consumption Space in an undisclosed US City. This is huge: nejm.org/doi/full/10.10… THREAD -
First of all, this is huge because the Safer Consumption Space exists and has existed for 6 yrs. A group of harm reduction activists and heroes (whose names we may never know) took action and started an underground SCS to save lives. They refused to wait. They acted.
Second of all, this is huge because the NEJM (a 'prestigious and exclusive journal') published a letter about this unsanctioned (read: illegal/controversial) SCS operating somewhere in the US. They provided a platform for the researchers to articulate and document the results.
Third of all, this is huge because it is a testament to the commitment that the harm reduction community has to providing results & evidence to support what we do (EVEN WHEN WE SHOULDN'T HAVE TO). I mean, these folks ran an underground site & still wanted to document results. 🤯
Now let's take a look at what they did, what they measured, and what we learned from this evaluation.

According to supplementary materials, the SCS was 2 rooms: 1 with 5/6 stations for injecting, 1 with a couch/chairs to chill out. Capped at 60 participants enrolled at any time
First 3 yrs was open 4-6hrs/day 5 days/week. Past 2 yrs, open 6-8hrs/day 5 days/week.

Though staff didn't help with injections, participants were allowed to help each other (THIS IS ALSO HUGE, bc no proposed legal sites would allow assisted injection).
Staff were available to monitor and respond to OD, used pulse oximeters to measure oxygen levels, administered naloxone, and monitored 60 minutes post-administration.
Here's a table summarizing # of injections per year (this increased over time) up to a total of 10,514 over 5 years. While a total of 33 overdoses occurred, all were reversed and managed on site with no calls for further medical emergency services. Image
SIDE BAR: Sometimes people talk about Safer Consumption Sites/Supervised Injection Facilities and say that they 'prevent overdoses.' This is not true. Overdoses still happen at these sites (toxic drug supply, vulnerability, etc) but overdose DEATHS are what we mean. Specify.
Here is a graph from the supplemental materials that shows how many injections occurred on site per month during the 5 years in the time frame. Show how extended hours increased utilization. (Read: if you open one, they will come. The longer they're open, the more they'll come) Image
Another extremely informative graph about drug types used, illustrating changing drug use trends and patterns over 5 years to more speedballs/goofballs. (Read: stop calling it an 'opioid' crisis already and let's talk abt drug mixing!) Image
Hope that's helpful! Please download the letter and the supplementary materials! They're open access!

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More from @MyHarmReduction

Sep 21, 2023
Thrilled to be here at the @MethadoneLib conference!

Great turnout in the room and I’m sure we have plenty folks logged in remotely representing so many diverse groups and regions!

We all share a commitment to #FreeMethadone!
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We are listening to an infuriating clip from @National_usu ‘s podcast Naturally Noncompliant to hear from people about their experiences and why we need to #FreeMethadone.

Follow and tune in podcasts.apple.com/us/podcast/nat…
@National_usu Moving onto our first panel with a fantastic lineup of speakers- @suenlw @DrChinazoOASAS Paul Joudrey @highway_dave and Kelly Knight!

#FreeMethadone Image
Read 6 tweets
May 10, 2023
People often ask, "What about treatment?" "Why aren't they in treatment?" when talking people with addictions or other mental health diagnoses.

We talk about treatment as some magical black box- people walk in sick and then walk out "better," improved, stabilized, asymptomatic.
But the reality is that treatment is slow and time-consuming.

Change does not happen overnight; it may not look how you expect.

The first days, weeks can be challenging. You settle in. You meet the counselors- some are great, some are terrible. You may not speak right away
Sure, there are lovely, warm. caring counselors. But there are shaming, blaming, harmful counselors too.

They may recognize you from the last time- some will welcome you back. Others will tell you, "I told you so."

There may be familiar faces in group therapy too. Good and bad.
Read 12 tweets
May 3, 2023
New CDC report on OD trends in US 2016 to 2021 🧵

- The US fentanyl-involved OD death rate is 21.6 per 100,000, a rate that more than TRIPLED in just 5 yrs
- Methamphetamine-involved OD death rate more than quadrupled,
- Cocaine rate more than doubled

🔗cdc.gov/nchs/data/vsrr… Image
- Meanwhile the rate of heroin-involved OD remained relatively stable during the 5 year period,
- Oxycodone-involved OD rate decreased by 20+%

**At this point, any talk of the overdose crisis without acknowledging prevalent stimulant use misses the mark
Gender disparities in overdose deaths remain so that men have significantly higher rates of overdose for all drugs compared to women.

Meanwhile middle-aged adults (aged 25-44) have incredibly high overdose death rates involving fentanyl Image
Read 8 tweets
Mar 8, 2023
Watching @CNN and @andersoncooper talking about the overdose crisis. They are talking about two tragic cases of young people who died of overdose with their grieving family members.

Both overdoses were with counterfeit pills. (1/?)
In first story, the young person thought it was a Percocet. When he was overdosing, a friend was deterred from calling 911 for fear of law enforcement.

In second story, the young man ODd while talking to his girlfriend on the phone but she didn’t know signs of him overdosing.
While they are talking about the need for more awareness of fentanyl adulteration, recognizing overdose, and naloxone access—tougher laws and prosecutions are also being proposed by family. They worry that felony charges for the dealer and 4 years in prison are not enough.
Read 28 tweets
Feb 25, 2023
Many people do not realize the difference between these terms and that they actually mean different things:

Decriminalization =/= Legalization =/= Regulation

These are three different things.

And only 1 of them ensures a known, tested, and monitored drug supply for all users.
1) Decriminalization simply means that possession is no longer a criminal offense.

You cannot get arrested, booked, finger printed.

No potential jail time.

Nothing on your record when you get a background check.

You may owe a fine. You may be diverted to a case worker.
+ You may be able to waive that fine if you complete a health assessment or see a dissuasion panel.

However, your drugs may be seized.

And, if they aren't seized, your drugs could still be adulterated or unsafe.

You may not know exactly what is in them.
Read 9 tweets
Nov 22, 2022
Learning from Dr. Joseph D'Orazio that xylazine is being detected in over 90% of tested heroin and fentanyl samples in Philadelphia.

Screenshot below shows that it's also prevalent in overdose victims - xylazine + fentanyl positive in 100% of those who died in 2020.
Also, Philadelphia seeing a notable trend of decreased benzodiazepine-involved overdose deaths while xylazine-involved overdose deaths are rising.
This slide shows that xylazine overdose response must prioritize airway management so they can breathe and keep in the recovery position.

Administering naloxone still important since opioids often still on board, yet may appear as a "narcan resistant OD" due to xylazine
Read 7 tweets

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