They mainly followed the WHO position
Along the way, some saw it as proof. It's not, but it does make you say "hmm.."
In this thread, I'm going to try and go much deeper into the data
The problem with Dr Raoult's early findings is that his patient base was fairly young so while his results were excellent, it was hard to evaluate them without a control
If anybody knows more, please share
Nobody knows HCQ works - antiviral/anti-inflammatory, they are all theories
Zinc - I know the theory and its scientifically plausible but nobody knows the exact mechanism
Michigan 2,541 patients retrospective
Treatment with HCQ cut the death rate significantly in sick hospitalized patients, no heart-related side-effects. HCQ decreases mortality from 26.4% to 13.5% (HCQ)
Kaplan-Meier estimate showed lower mortality in hospitalized patients who received hydroxychloroquine (log rank Pvalue < 0.001)
Results: 77 (0.29%) of 26,815 C19 positive patients and 1,215 (0.36%) of 333,489 negative patients were chronically treated with HCQ (P=0.04)
Conclusions: data suggest that chronic treatment with HCQ confer protection against C19 infection
This is the infamous VA retrospective study where the HCQ arm was significantly sicker
This got huge headlines
1) did a crazy propensity matching to align two arms which barely overlapped
2) conflated intubation or death into a single outcome but didn't provide seperate numbers
WHO recommended an end to HCQ use based on this study which later had to be retracted, because the data was allegedly fake
The negative studies are mostly about treating very sick patients with HCQ which is known not 2 work
I believe there is some amount of bad faith involved here
It has been 4 months and we do not have one proper RCT study...
1) differences caused by the introduction of HCQ into a population previously not receiving it
2) early treatment protocols in countries that significantly outperform other countries with similar age pyramids
If comparing countries with similar age pyramids and testing, significant differences can indicate that treatment is a significant factor
According to one infectious disease specialist, "near-total effectiveness."
Russia's treatment protocol: Treat early and often with HCQ
This was hard to find, but here are Ukraine's treatment protocols - immediate treatment upon suspicion of Covid
HCQ Studies are overwhelmingly positive
Negative studies get lots of attention but have some serious flaws
Country data offers some convincing arguments
Need to wait for RCTs to be proven
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Draw your own conclusions
I hear there are plenty of volunteers to populate (30k) Moderna’s mRNA vaccine trial