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#IdBoardReview 30 M injection drug use, hx of MRSA IE s/p tricuspid/mitral valve repair 1 year ago now presents with weakness, chills, BC+GPC w/ aerobic sticky staph-like white-gray colonies. TEE+TV vegetation. pathogen? #idmedEd #medEd
#Rothia mucilaginosa endocarditis
#Rothia mucilaginosa is increasingly recognized as an emerging opportunistic pathogen associated with prosthetic device infections. Gram-positive cocci, catalase negative, sticky “staph-like” colonies whitish to gray in color, nonhemolytic, smooth, and round
R. mucilaginosa normal inhabitant of human oral cavity & respiratory tract. Infrequent pathogen, mostly in immunocompromised hosts (cancer, severe neutropenia, HIV, alcoholism, diabetes mellitus & chronic liver disease)
Risk factors for #Rothia injection drug use, cardiac valve disease, prosthetic devices. Infections: bacteremia, endovascular infection, CNS infection, ocular infection, B&J infection, pulmonary infection, biliary tract infection, SSTI
#Rothia generally susceptible to penicillin/ampicillin, cefotaxime, imipenem, rifampin & vancomycin. Frequently resistant to clindamycin, AG, tmp-smx, FQ.
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