First tobacco use ≤13 yo associated with daily and past 30-day use of non-cigarette tobacco products and nicotine dependence.
Increased risk of nicotine dependence in those who start in early adolescence
Adolescents and young adults disproportionately develop EVALI.
Adolescents with EVALI more frequently have a history of asthma and mental, emotional, or behavioral disorders, such as ADHD
Use of e-cigs increases the risk of future cigarette use.
Effect is increased in youths felt to be low risk for future addiction.
Both high and low levels of e-cigarette use patterns are associated with increasing use of other substances (alcohol and marijuana use) over time.
Varenicline plus brief counseling did not promote long-term cessation in teens/young adults but may hasten abstinence.