☠ #LeadPoisoning
👉Abdominal pain, microcytic anemia, basophilic stippling, polyneuropathy, encephalopathy, seizures
💧 Basophilic stippling: Basophilic granules of RNA seen in RBC; arsenic poisoning, sideroblastic anemia, myelodysplastic syndrome, thalassemia, others
👉Abdominal pain, microcytic anemia, basophilic stippling, polyneuropathy, encephalopathy, seizures
💧 Basophilic stippling: Basophilic granules of RNA seen in RBC; arsenic poisoning, sideroblastic anemia, myelodysplastic syndrome, thalassemia, others
⚠️Diagnosis: blood lead level (BLL) , basophilic stippling, microcytic-hypochromic anemia, patient's exposure history
⛔Exposure: Ayurvedic therapies, herbal supplements, glazed ceramic cookware, lead-contaminated opium (majority of illicit opium comes from Afghanistan)
⛔Exposure: Ayurvedic therapies, herbal supplements, glazed ceramic cookware, lead-contaminated opium (majority of illicit opium comes from Afghanistan)
💊 Rx: decrease exposure, nutrition, chelation therapy (oral succimer with/without intravenous or intramuscular CaNa2EDTA when BLL ≥ 80 μg/dL)
ABCDEFGH –
Anemia
Basophilic stippling
Colic
Diarrhea
Encephalopathy
Foot drop
Gum deposition/Growth retardation/Gout Hyperuricemia/Hypertension
📚
1.nejm.org/doi/full/10.10…
2.nejm.org/doi/full/10.10…
Anemia
Basophilic stippling
Colic
Diarrhea
Encephalopathy
Foot drop
Gum deposition/Growth retardation/Gout Hyperuricemia/Hypertension
📚
1.nejm.org/doi/full/10.10…
2.nejm.org/doi/full/10.10…
